DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18735 and tmprss15

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_001919639.2	Gene:	tmprss15 / 100148042	ZFINID:	ZDB-GENE-091204-83	Length:	990	Species:	Danio rerio

Alignment Length:	264	Identity:	101/264 - (38%)
Similarity:	144/264 - (54%)	Gaps:	23/264 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 PAKRECAECSCGNINTRHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCVNGF 128
            |:|.:..|.:.|  ....|:||||:.:...:|||:.|.|.|...|||:|::.::.:||||||.|.
Zfish   731 PSKSKIIEETDG--KKEGRVVGGQDAQRGAWPWMVSLQWLGGHACGATLIDREWLITAAHCVYGR 793

  Fly   129 YHRL----------ITVRLLEHNRQDSHVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRL 183
            ..:|          .....:..|:|   |..||    :|::|..|:.|..:||.||:....||..
Zfish   794 NVQLSNWAAVLGLHAQFETINPNKQ---VFSVD----QVIMHKHYNKRTKESDFALMHLKTPVSY 851

  Fly   184 GIDMHPVCMPTPSENY-AGQTAVVTGWGALSEGGPISDTLQEVEVPILSQEECRNSNYGESKITD 247
            ...:.|:|:|.|..:: .|:...:.|||.|||.|..:|.||:..||:||..:|:.. ..|...|:
Zfish   852 TDYVQPICLPDPGAHFEEGRKCFIAGWGLLSESGLKADVLQQAVVPLLSNTQCQEW-LPEYNFTE 915

  Fly   248 NMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWIA 312
            .|:||||.| ||.|:||||||||:.....|. :.|.|..|:|.||.:|..||.|.||..|.||:|
Zfish   916 RMMCAGYAE-GGVDTCQGDSGGPLMCEEEGH-WVLVGATSFGIGCGRPQRPGAYARVSQFVDWVA 978

  Fly   313 ENTR 316
            ||.|
Zfish   979 ENRR 982

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	92/239 (38%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	93/241 (39%)
tmprss15	XP_001919639.2	SEA	19..>89	CDD:279699
		LDLa	142..175	CDD:238060
		CUB	183..288	CDD:238001
		MAM	302..457	CDD:279023
		MAM	302..457	CDD:99706
		CUB	477..586	CDD:238001
		LDLa	596..630	CDD:238060
		SRCR_2	653..728	CDD:295335
		Tryp_SPc	747..977	CDD:214473	92/239 (38%)
		Tryp_SPc	748..980	CDD:238113	93/241 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6379
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3952
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.840