DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18735 and masp1

DIOPT Version :9

Sequence 1:	NP_652645.1	Gene:	CG18735 / 59137	FlyBaseID:	FBgn0042098	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_001373185.1	Gene:	masp1 / 100002060	ZFINID:	ZDB-GENE-110421-4	Length:	740	Species:	Danio rerio

Alignment Length:	312	Identity:	97/312 - (31%)
Similarity:	152/312 - (48%)	Gaps:	73/312 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 GPEVPAEWSSPAKRECAECSCGNINT-----RHRIVGGQETEVHEYPWMIML-----------MW 102
            |||.|...:|      ...:||..:.     :.|||||:......:||.::|           .|
Zfish   438 GPESPTPLAS------TPLACGEQSQPFPAHQKRIVGGRPASPGLFPWQVLLSVEDVYRVPVVRW 496

  Fly   103 FGNFYCGASLVNDQYALTAAHCVNGFYHRL-ITVRLLEHNRQDSHVKIVD---------RRVSRV 157
            ||:    .:|::..:.:||||.:..  ||| ::|..::......|:.:.|         |.|.::
Zfish   497 FGS----GALLSPLWIVTAAHVLRS--HRLDLSVVPVDPEHIQVHLGLTDVRQKHLATNRSVEKI 555

  Fly   158 LIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPVCMPTP-------SENYAGQTAVVTGW------ 209
            ::||::..:|:::||||::.|:.|.|...:.|||:|.|       :.|..|   :|.||
Zfish   556 ILHPQFDPQNYNNDIALVKLNQEVALSALVRPVCLPRPGLDSQVLTPNTLG---IVAGWGINAAN 617

  Fly   210 ------GALSEGGPISDTLQEVEVPILSQEEC------RNSNYGESKITDNMICAGYVEQGGKDS 262
                  |..|:...:|:.||.|::|::||:||      |:.||   .||.||.|||:.| ||:|:
Zfish   618 ASASSSGLTSDSSSVSELLQYVKLPVVSQDECEASYASRSVNY---NITGNMFCAGFYE-GGQDT 678

  Fly   263 CQGDSGGPMHVL-GSGDAYQLAGIVSWG--EGCAKPNAPGVYTRVGSFNDWI 311
            |.|||||..... |....:...|:||||  |.|......||||||.::..|:
Zfish   679 CLGDSGGAFVTQDGRSGRWVAHGLVSWGGPEECGSQRVYGVYTRVANYLQWL 730

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18735	NP_652645.1	Tryp_SPc	82..311	CDD:214473	89/277 (32%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	89/278 (32%)
masp1	NP_001373185.1	CUB	29..135	CDD:214483
		FXa_inhibition	143..181	CDD:405372
		CUB	189..294	CDD:395345
		PHA02639	<300..>425	CDD:165022
		Sushi	301..362	CDD:395037
		Tryp_SPc	465..729	CDD:214473	89/276 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910