Protein Alignment RAP1GAP and gig

DIOPT Version :9

• Sequence 1: NP_001375129.1
• Gene: RAP1GAP / 5909
• HGNCID: 9858
• Length: 842
• Species: Homo sapiens
• Sequence 2: NP_524177.1
• Gene: gig / 40201
• FlyBaseID: FBgn0005198
• Length: 1847
• Species: Drosophila melanogaster
• Alignment Length: 326
• Identity: 69/326 - (21%)
• Similarity: 125/326 - (38%)
• Gaps: 92/326 - (28%)

Human   180 LIVTFDEHVISNNFKFGVIYQKLGQTSEE-ELFSTNEESPAFVEFLEFLGQKVKLQDFKGFRGGL 243
            |:..|:.|      |.||:|...||.:.| |:...:..|..:||||..:|..|.|::.:  :..|
  Fly  1591 LVPPFETH------KIGVLYVGQGQCNNEVEILRNSHGSARYVEFLRNIGTLVSLKEAE--QNNL 1647

Human   244 DVTHGQTGTESVYCNFRNKEIM---FHVSTKLPYT-EGDAQQLQRKRHIGNDIVAVVFQDENTPF 304
            .:...:.|.:..:......:|:   |||:|.:|.. :.|....::|.|||||.|.:::.:....:
  Fly  1648 FIMLDRNGADGKFAYIWKDDILQVTFHVATLMPTNLQDDPNCNEKKSHIGNDFVKIIYNESGEEY 1712

Human   305 VPDMIASNFLHAYVVVQAEGGGPDGPL----YKVSVTARDDVPFFGPPLPDPAVFRKGPEFQEFL 365
            ..:.|:..|.:|.|:|:        ||    .:|.|.||.::..|
  Fly  1713 NLNTISGQFNYACVIVE--------PLDLNSNRVYVKARSEISKF-------------------- 1749

Human   366 LTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMENGSGGGGFFES 430
               :.:|||... :::.|.|..|..|         ||.:..|::    .:...:.......:.|.
  Fly  1750 ---VCHAEYRIV-SDRSAPLLARQMA---------LHANLASLV----YQSVQKKHPYASNWLER 1797

Human   431 FKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLLIPGKSASRFGRRGSAI 495
            .:::.|.||:.::.:....|.                              |.::|..|...|||
  Fly  1798 LRKLKRLRSKLIEGLNSQQKS------------------------------GSASSGIGINASAI 1832

Human   496 G 496
            |
  Fly  1833 G 1833

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAP1GAP	NP_001375129.1	GoLoco	<1..17	CDD:214645
		Rap_GAP	211..390	CDD:396632	42/186 (23%)
gig	NP_524177.1	DUF3384	40..467	CDD:288697
		HEAT repeat	484..515	CDD:293787
		Tuberin	566..882	CDD:281532
		Rap_GAP	1617..1802	CDD:280332	47/231 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1559
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.940