Protein Alignment RAP1B and Rgk3

DIOPT Version :10

• Sequence 1: NP_056461.1
• Gene: RAP1B / 5908
• HGNCID: 9857
• Length: 184
• Species: Homo sapiens
• Sequence 2: NP_001286670.1
• Gene: Rgk3 / 5740446
• FlyBaseID: FBgn0085426
• Length: 486
• Species: Drosophila melanogaster
• Alignment Length: 194
• Identity: 59/194 - (30%)
• Similarity: 90/194 - (46%)
• Gaps: 37/194 - (19%)

Human     4 YKLVVLGSGGVGKSALTVQFVQGIFVEKYD-PTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAM 67
            |::.:|||.||||.||..||.....:..|| |..:         ||:|.:..||:  |||  :.:
  Fly   235 YRVEMLGSAGVGKQALLSQFRTSDCINAYDGPECD---------DAEQNVSIILN--GTE--SEL 286

Human    68 RDL--------YMKNGQGFALVYSITAQSTFNDLQDLREQIL-RVKDTDDV---PMILVGNKCDL 120
            :.|        .::....|.:|||...:.:|.    ..:||| |::|.|.:   |.|||.||.||
  Fly   287 KFLTGNPESKDELEQADAFLVVYSCIDKESFT----RAKQILSRLQDMDLLRHRPTILVANKIDL 347

Human   121 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQIN-RKTPV-----PGKARKK 178
            ...|.|..:.|:.:|..: ...|:|.|.....|.:|:....:.||. :|..|     |.|::.|
  Fly   348 ARSRAVSAQDGKCVACTF-GAKFIEVSVGINHNCDELLAGTLTQIRLKKDQVQLQLNPKKSKDK 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAP1B	NP_056461.1	Rap1	3..167	CDD:133375	54/176 (31%)
		Interaction with KRIT1. /evidence=ECO:0000269|PubMed:22577140	25..67		11/42 (26%)
		Effector region. /evidence=ECO:0000305	32..40		3/8 (38%)
Rgk3	NP_001286670.1	P-loop containing Nucleoside Triphosphate Hydrolases	235..>396	CDD:476819	54/178 (30%)