Protein Alignment RAP1B and Rala

DIOPT Version :10

• Sequence 1: NP_056461.1
• Gene: RAP1B / 5908
• HGNCID: 9857
• Length: 184
• Species: Homo sapiens
• Sequence 2: NP_525063.1
• Gene: Rala / 31332
• FlyBaseID: FBgn0015286
• Length: 201
• Species: Drosophila melanogaster
• Alignment Length: 191
• Identity: 90/191 - (47%)
• Similarity: 135/191 - (70%)
• Gaps: 11/191 - (5%)

Human     4 YKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMR 68
            :|::::|||||||||||:||:...|||.|:||..|||||:|.:|.::..::||||||.|.:.|:|
  Fly    12 HKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIR 76

Human    69 DLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQN 133
            |.|.::|:||..|:|||...:|...|:.||||||||:.:.:|.:||||||||.|:|.|...:.|.
  Fly    77 DNYFRSGEGFLCVFSITDDESFQATQEFREQILRVKNDESIPFLLVGNKCDLNDKRKVPLSECQL 141

Human   134 LARQWNNCAFLESSAKSKINVNEIFYDLVRQI-NRKT----PVPGKA-----RKKSSCQLL 184
            .|:|| ...::|:|||::.||:::|:||:|:| :|||    ...|:|     :::..|.||
  Fly   142 RAQQW-AVPYVETSAKTRENVDKVFFDLMREIRSRKTEDSKATSGRAKDRCKKRRLKCTLL 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAP1B	NP_056461.1	Rap1	3..167	CDD:133375	82/163 (50%)
		Interaction with KRIT1. /evidence=ECO:0000269|PubMed:22577140	25..67		20/41 (49%)
		Effector region. /evidence=ECO:0000305	32..40		4/7 (57%)
Rala	NP_525063.1	RalA_RalB	12..174	CDD:206710	82/162 (51%)