Protein Alignment RAP1A and Rgk3

DIOPT Version :10

• Sequence 1: NP_002875.1
• Gene: RAP1A / 5906
• HGNCID: 9855
• Length: 184
• Species: Homo sapiens
• Sequence 2: NP_001286670.1
• Gene: Rgk3 / 5740446
• FlyBaseID: FBgn0085426
• Length: 486
• Species: Drosophila melanogaster
• Alignment Length: 196
• Identity: 58/196 - (29%)
• Similarity: 89/196 - (45%)
• Gaps: 42/196 - (21%)

Human     4 YKLVVLGSGGVGKSALTVQFVQGIFVEKYD-PTIEDSYRKQVEVDCQQCMLEILDTAGTEQFTAM 67
            |::.:|||.||||.||..||.....:..|| |..:|:         :|.:..||:  |||  :.:
  Fly   235 YRVEMLGSAGVGKQALLSQFRTSDCINAYDGPECDDA---------EQNVSIILN--GTE--SEL 286

Human    68 RDL--------YMKNGQGFALVYSITAQSTF-------NDLQDLREQILRVKDTEDVPMILVGNK 117
            :.|        .::....|.:|||...:.:|       :.|||:  .:||.:     |.|||.||
  Fly   287 KFLTGNPESKDELEQADAFLVVYSCIDKESFTRAKQILSRLQDM--DLLRHR-----PTILVANK 344

Human   118 CDLEDERVVGKEQGQNLARQWC--NCAFLESSAKSKINVNEIFYDLVRQIN-RKTPVEKKKPKKK 179
            .||...|.|..:.|:.:|   |  ...|:|.|.....|.:|:....:.||. :|..|:.:...||
  Fly   345 IDLARSRAVSAQDGKCVA---CTFGAKFIEVSVGINHNCDELLAGTLTQIRLKKDQVQLQLNPKK 406

Human   180 S 180
            |
  Fly   407 S 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAP1A	NP_002875.1	Rap1	3..167	CDD:133375	53/181 (29%)
		Effector region. /evidence=ECO:0000305	32..40		4/8 (50%)
Rgk3	NP_001286670.1	P-loop containing Nucleoside Triphosphate Hydrolases	235..>396	CDD:476819	53/183 (29%)