Protein Alignment RAP1A and kappaB-Ras

DIOPT Version :10

• Sequence 1: NP_002875.1
• Gene: RAP1A / 5906
• HGNCID: 9855
• Length: 184
• Species: Homo sapiens
• Sequence 2: NP_610278.1
• Gene: kappaB-Ras / 35667
• FlyBaseID: FBgn0040513
• Length: 201
• Species: Drosophila melanogaster
• Alignment Length: 179
• Identity: 50/179 - (27%)
• Similarity: 85/179 - (47%)
• Gaps: 15/179 - (8%)

Human     5 KLVVLGSGGVGKSALTVQFVQGIFVEKYD--PTIEDSYRKQVEV--DCQQCMLEILDTAGT--EQ 63
            |::|.|..||||:||..|.|.|....:.:  |||||.|...|:.  ...:..|.|.||||.  ||
  Fly    11 KVLVCGMKGVGKTALIEQLVYGHVNPETELHPTIEDIYVASVDTGRGGARETLRIYDTAGLQGEQ 75

Human    64 FTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGK 128
            ....|. |::....|.|||......:.:.|.|::..|.:.|:.:::|::::.|.........|
  Fly    76 QQLPRH-YLQFPDAFVLVYDPMDPRSLDMLADIKADIEKHKEKKEIPVVVLANVRARAAPNPV-- 137

Human   129 EQGQNLARQWCNCAFLES---SAKSKINVNEIFYDLVRQINRKTPVEKK 174
            |:..:.|..||....::.   :|..:.::.|.|..|..:::   |::.|
  Fly   138 EKVMDRANIWCQRERIKHYTVNAMERPSLYEPFTTLCARLH---PMQTK 183

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAP1A	NP_002875.1	Rap1	3..167	CDD:133375	48/170 (28%)
		Effector region. /evidence=ECO:0000305	32..40		5/9 (56%)
kappaB-Ras	NP_610278.1	Ras_like_GTPase	13..174	CDD:206648	46/163 (28%)