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Protein Alignment BCHE and CG4382

DIOPT Version :9

Sequence 1:	NP_000046.1	Gene:	BCHE / 590	HGNCID:	983	Length:	602	Species:	Homo sapiens
Sequence 2:	NP_609301.2	Gene:	CG4382 / 34279	FlyBaseID:	FBgn0032132	Length:	580	Species:	Drosophila melanogaster

Alignment Length:	606	Identity:	179/606 - (29%)
Similarity:	281/606 - (46%)	Gaps:	99/606 - (16%)

- Green bases have known domain annotations that are detailed below.

Human    11 RFLFWFLLLCMLI-GKSHTED-------------------DIIIATKNGKVRGMNL-TVFGGTVT 54
            |...:.||||.|. |::..||                   |::|.|..||:||..| :..|....
  Fly     3 RLCGFVLLLCGLASGQNSDEDLSKAIPDEEDPIGSNKELSDLVITTALGKIRGTILPSQSGRNFY 67

Human    55 AFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSED 119
            ||.|||||:||:.||||:.|:.:.:|.|             .:|.:|.|....::...:.|:|||
  Fly    68 AFRGIPYAKPPVDRLRFQPPEPVEQWFD-------------TLDATFDGPKCPQLGLVSGDVSED 119

Human   120 CLYLNVW---IPAPKPKNA--TVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGAL 179
            ||.:|::   :|:....|.  .|:::|:.|||.:.:.....:.|.......|:::|:.|||:|:|
  Fly   120 CLRVNIYTKELPSESQPNVRRPVIVFIHPGGFYSLSGQSKNFAGPQYFMNRRLVLVTFNYRLGSL 184

Human   180 GFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSL 244
            |||| .|..||||||||.||...|:||:.:|:.|||:|.|:||.|..|||.:|:||::||.|..|
  Fly   185 GFLA-TGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPSSITLLGYGAGAMAVTLHMVSPMSRGL 248

Human   245 FTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEI--LLNEAFV 307
            |.:||:.||:....|::..  ...:.....|.|..|..||.||::.||:.|...|.  .|.:.|.
  Fly   249 FHKAIVMSGAVTGQWSLPD--HQMDVATKQATLLHCHTENVTEMMDCLKGKHYLEFANTLPKMFE 311

Human   308 VPYGTPLSVNFGPTVDGD-----FLTDMPDILLELGQFKKTQILVGVNKDE--GTAFLVYGAPGF 365
            .....|| :.:.|.::.|     ||.:.|....:...|.|..|:.|:.|||  |.|..:..:|..
  Fly   312 FDRNNPL-ILWKPVIEPDFGQERFLVEEPIRSYQNDDFMKVPIITGMTKDEFVGPALSILQSPTL 375

Human   366 SKDNNSIITRKEFQEGLKIFFPGVSEFGK-----ESILFHY--TDWVDDQRPENYREALGDVVGD 423
            ....|     :.|:....:||...:...:     :.:..||  ...:|..|.   .|||.::..|
  Fly   376 LSALN-----ENFESLAPVFFMYNTSDARACNISQELRNHYFPDKLIDANRS---LEALSNLYSD 432

Human   424 -------YNFICPALEFTK----KFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLP 477
                   :.|:..|...||    :||..|..:..||.|    ..|:    ||:|..::.::|..|
  Fly   433 ALTGFGIHRFVHLAARSTKVYYYRFSYQGARSHIYYPE----DAPY----GVVHHDDLMYLFVEP 489

Human   478 LERR-----DNYTKAEEILSRSIVKRWANFAKYGNPNETQN---NSTSWPVFKSTEQKYLTLNTE 534
            ...|     |:..:..:|:    |:.::.||..|:||:..:   ....|..|...::.||.:...
  Fly   490 SISRMFTEDDDEFRMVDIM----VRMFSAFAYKGDPNKPTDLALRDIRWRPFSFKKRYYLDIGKH 550

Human   535 STRIMTKLRAQQCRFWTSFFP 555
            .| :...|.|:....|...||
  Fly   551 IT-LEENLNAENYEIWKRLFP 570

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.