DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RALA and Rala

DIOPT Version :9

Sequence 1:	NP_005393.2	Gene:	RALA / 5898	HGNCID:	9839	Length:	206	Species:	Homo sapiens
Sequence 2:	NP_525063.1	Gene:	Rala / 31332	FlyBaseID:	FBgn0015286	Length:	201	Species:	Drosophila melanogaster

Alignment Length:	194	Identity:	155/194 - (79%)
Similarity:	170/194 - (87%)	Gaps:	2/194 - (1%)

- Green bases have known domain annotations that are detailed below.

Human    13 ALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAA 77
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Fly    10 ALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAA 74

Human    78 IRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDLEDKRQVSVEEA 142
            |||||||||||||||||||:.|||.||.:|||||||||.||::||||||||.||.|||:|.:.|.
  Fly    75 IRDNYFRSGEGFLCVFSITDDESFQATQEFREQILRVKNDESIPFLLVGNKCDLNDKRKVPLSEC 139

Human   143 KNRAEQWNVNYVETSAKTRANVDKVFFDLMREIRARKMEDSKEKNGKKKRKSLAKRIRERCCIL 206
            :.||:||.|.|||||||||.||||||||||||||:||.||||..:|:.|.:  .|:.|.:|.:|
  Fly   140 QLRAQQWAVPYVETSAKTRENVDKVFFDLMREIRSRKTEDSKATSGRAKDR--CKKRRLKCTLL 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RALA	NP_005393.2	RalA_RalB	15..177	CDD:206710	140/161 (87%)
RALA	NP_005393.2	Effector region	43..51		7/7 (100%)
Rala	NP_525063.1	RalA_RalB	12..174	CDD:206710	140/161 (87%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	279	1.000	Domainoid score	I1704
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3942
Inparanoid	1	1.050	304	1.000	Inparanoid score	I2662
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1259506at2759
OrthoFinder	1	1.000	-	-		FOG0002545
OrthoInspector	1	1.000	-	-		otm41018
orthoMCL	1	0.900	-	-		OOG6_104721
Panther	1	1.100	-	-	LDO	PTHR24070
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3397
SonicParanoid	1	1.000	-	-		X1669
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.860