DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MOK and Mok

DIOPT Version :9

Sequence 1:	NP_055041.1	Gene:	MOK / 5891	HGNCID:	9833	Length:	419	Species:	Homo sapiens
Sequence 2:	XP_038968482.1	Gene:	Mok / 362787	RGDID:	1309274	Length:	435	Species:	Rattus norvegicus

Alignment Length:	416	Identity:	350/416 - (84%)
Similarity:	377/416 - (90%)	Gaps:	1/416 - (0%)

- Green bases have known domain annotations that are detailed below.

Human     3 NYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNNLREIQALRRLNPHPNILMLH 67
            :|||||||||||||||:||||||||||||||||||.||||||||||||||||||||||||||.||
  Rat    19 DYKAIGKIGEGTFSEVLKMQSLRDGNYYACKQMKQHFESIEQVNNLREIQALRRLNPHPNILTLH 83

Human    68 EVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHIHRNGIFHRDVKPE 132
            ||||||||||||||||||||||||||||||:||||||||||||||||||||:|||||||||||||
  Rat    84 EVVFDRKSGSLALICELMDMNIYELIRGRRHPLSEKKIMHYMYQLCKSLDHMHRNGIFHRDVKPE 148

Human   133 NILIKQDVLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFYTYKMDLWSAGCVFYEIAS 197
            |||:|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   149 NILVKQDVLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFYTYKMDLWSAGCVFYEIAS 213

Human   198 LQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRAMNFDFPFKKGSGIPLLTTNLSPQCLSLL 262
            ||||||||||||||||||||||||.||.||||||||||:||||||||||||||||||:|||||||
  Rat   214 LQPLFPGVNELDQISKIHDVIGTPCQKTLTKFKQSRAMSFDFPFKKGSGIPLLTTNLTPQCLSLL 278

Human   263 HAMVAYDPDERIAAHQALQHPYFQEQRKTEKRALGSHRKAGFPEHPVAPEPLSNSCQISKEGRKQ 327
            ||||||||||||||||||||||||.||..|.:.|..||:|.:|::.:.||..|::...|||||||
  Rat   279 HAMVAYDPDERIAAHQALQHPYFQVQRAAETQTLAKHRRAFYPKYSMVPESSSHNWSFSKEGRKQ 343

Human   328 KQSLKQEEDRPKRRGPAYVMELPKLKLSGVVRLSSYSSPTLQSVLGSGTNGRVPVLRPLKCIPAS 392
             |.|:|||.|.:|:||..:.|||||:|||:.:|||.|||.|:||||:|.||||||||||||...:
  Rat   344 -QPLRQEEGRARRQGPTSLTELPKLRLSGMTKLSSCSSPALRSVLGTGANGRVPVLRPLKCAVVN 407

Human   393 KKTDPQKDLKPAPQQCRLPTIVRKGG 418
            ||||.|||:||..:.|.||||.||||
  Rat   408 KKTDTQKDIKPHLKHCHLPTINRKGG 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MOK	NP_055041.1	STKc_MOK	4..285	CDD:270825	270/280 (96%)
		S_TKc	4..285	CDD:214567	270/280 (96%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	285..344		28/58 (48%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	390..419		18/29 (62%)
Mok	XP_038968482.1	STKc_MOK	20..301	CDD:270825	270/280 (96%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83685093
Domainoid	1	1.000	567	1.000	Domainoid score	I5466
eggNOG	1	0.900	-	-		E1_KOG0661
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8062
Inparanoid	1	1.050	723	1.000	Inparanoid score	I8504
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG56365
OrthoDB	1	1.010	-	-		D102749at40674
OrthoFinder	1	1.000	-	-		FOG0012472
OrthoInspector	1	1.000	-	-		oto132745
orthoMCL	1	0.900	-	-		OOG6_104700
Panther	1	1.100	-	-	LDO	PTHR24055
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X10424
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	17	17.310