Protein Alignment RAD51B and RAD51

DIOPT Version :10

• Sequence 1: NP_001308750.1
• Gene: RAD51B / 5890
• HGNCID: 9822
• Length: 425
• Species: Homo sapiens
• Sequence 2: NP_011021.3
• Gene: RAD51 / 856831
• SGDID: S000000897
• Length: 400
• Species: Saccharomyces cerevisiae
• Alignment Length: 346
• Identity: 95/346 - (27%)
• Similarity: 158/346 - (45%)
• Gaps: 34/346 - (9%)

Human     1 MGS----KKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELLCMVSRACA 61
            :||    :||:..|::.....:|....:.|.:........:|:::.|:|.....:||...:|...
Yeast    77 LGSFVPIEKLQVNGITMADVKKLRESGLHTAEAVAYAPRKDLLEIKGISEAKADKLLNEAARLVP 141

Human    62 PKMQTAYGIKAQRSADFSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFCIMMSILAT 126
            ....||.....:||   ....|:|....||..|.|||..||:||:.|....||:|.|..:::...
Yeast   142 MGFVTAADFHMRRS---ELICLTTGSKNLDTLLGGGVETGSITELFGEFRTGKSQLCHTLAVTCQ 203

Human   127 LPTNMGGLEGAVVYIDTESAFSAERLVEIAESRFPRYFNTEEKLLLTSSKVHLYRELTCDEVLQR 191
            :|.::||.||..:|||||..|...|||.||: ||.  .:.::.|    :.|...|....|..|:.
Yeast   204 IPLDIGGGEGKCLYIDTEGTFRPVRLVSIAQ-RFG--LDPDDAL----NNVAYARAYNADHQLRL 261

Human   192 IESLEEEIISKGIKLVILDSVASVVRKEFDAQLQGNLKERNKFLAREASSLKYLAEEFSIPVILT 256
            :::..:.:......|:::|||.::.|.:|..  :|.|..|...||:...:|:.||::|.:.|::|
Yeast   262 LDAAAQMMSESRFSLIVVDSVMALYRTDFSG--RGELSARQMHLAKFMRALQRLADQFGVAVVVT 324

Human   257 NQITTHLSGALASQADLVSPADDLSLSEGTSGSSCVIAALGNTWSHSVNTRLILQYLDSERRQIL 321
            ||:...:.|.:|...|...|..                  ||..:||..|||..:.....:|...
Yeast   325 NQVVAQVDGGMAFNPDPKKPIG------------------GNIMAHSSTTRLGFKKGKGCQRLCK 371

Human   322 IAKSPLAPFTSFVYTIKEEGL 342
            :..||..|....|:.|.|:|:
Yeast   372 VVDSPCLPEAECVFAIYEDGV 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAD51B	NP_001308750.1	Rad51B	91..327	CDD:410901	69/235 (29%)
RAD51	NP_011021.3	recomb_RAD51	83..397	CDD:274048	93/340 (27%)