Protein Alignment RAD51B and RAD57

DIOPT Version :10

• Sequence 1: NP_001308750.1
• Gene: RAD51B / 5890
• HGNCID: 9822
• Length: 425
• Species: Homo sapiens
• Sequence 2: NP_010287.1
• Gene: RAD57 / 851567
• SGDID: S000002411
• Length: 460
• Species: Saccharomyces cerevisiae
• Alignment Length: 379
• Identity: 98/379 - (25%)
• Similarity: 148/379 - (39%)
• Gaps: 118/379 - (31%)

Human    29 DFLCLSPLELMKVTGLSYRG--------VHELLCMVSRACAPKMQTAYGIKAQRSADFSPAFLST 85
            |||.|:|.||.::...|...        |||........|.         |...|.|..|...:|
Yeast    47 DFLTLTPKELARLIQRSINEVFRFQQLLVHEYNEKYLEICE---------KNSISPDNGPECFTT 102

Human    86 TLSALDEALHGGVACGSLTEITGPPGCGKTQFCIMMSILATLPTNMGGLEGAVVYIDTESAFSAE 150
            ...|:||.|.||:....:|||.|....||:|..:.:::...|....|||.|..|||.||.....:
Yeast   103 ADVAMDELLGGGIFTHGITEIFGESSTGKSQLLMQLALSVQLSEPAGGLGGKCVYITTEGDLPTQ 167

Human   151 RLVEIAESRFPRYFNTEEKLLLTSSKVHLYRELTCDEVLQRIESLEEEII----------SKG-I 204
            ||..:..|| |.|    |||.:|.|.:.   .::|::::.     :|.||          ||| |
Yeast   168 RLESMLSSR-PAY----EKLGITQSNIF---TVSCNDLIN-----QEHIINVQLPILLERSKGSI 219

Human   205 KLVILDSVASVVRKEFDAQLQGNLKERNKFLAREASSLKYLAEEFSIPVILTNQI---------T 260
            ||||:||::..:|.|...:.....:|...:|.|.|..|:.||.::|:.|::.||:         .
Yeast   220 KLVIIDSISHHLRVELQNKSFRESQENKNYLDRMAEKLQILAHDYSLSVVVANQVGDKPLANSPV 284

Human   261 TH-----------------------------LSGALASQADLVSPADDLSLSEGT---------- 286
            .|                             |.||.::..:::|..:|..|.|..
Yeast   285 AHRTYVTDYDYQLGWLVGWKNSTILYRQMNSLLGASSNNDEILSDDEDYMLIERVMSTVNDRNYD 349

Human   287 -----------------SGSSCV------------IAALGNTWSHSVNTRLILQ 311
                             :.||.:            :..||.|||:.|:||::||
Yeast   350 FFSKKKPPIIENKTVERNSSSPISRQSKKRKFDYRVPNLGLTWSNHVSTRILLQ 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAD51B	NP_001308750.1	Rad51B	91..327	CDD:410901	80/309 (26%)
RAD57	NP_010287.1	XRCC3	107..445	CDD:410899	80/310 (26%)