Protein Alignment RAD51B and rad51c

DIOPT Version :10

• Sequence 1: NP_001308750.1
• Gene: RAD51B / 5890
• HGNCID: 9822
• Length: 425
• Species: Homo sapiens
• Sequence 2: NP_001016923.1
• Gene: rad51c / 548416
• XenbaseID: XB-GENE-1015191
• Length: 361
• Species: Xenopus tropicalis
• Alignment Length: 394
• Identity: 114/394 - (28%)
• Similarity: 173/394 - (43%)
• Gaps: 90/394 - (22%)

Human    26 TCQDFLCLSPLELMKVTGLSYRGVHELLCMV------SRAC-APKMQTAYGIKAQRSADFSPAFL 83
            |.:..|..|.:||.|..|:|.....|:|.:|      |.:| ..:..||:.:..|..   |..|:
 Frog    25 TVETILEFSAVELSKEAGISNEEALEVLQIVKGEAQSSSSCQIIQKHTAFDLLGQEQ---SQGFV 86

Human    84 STTLSALDEALHGGVACGSLTEITGPPGCGKTQFCIMMSILATLPTNMGGLEGAVVYIDTESAFS 148
            .|..|||||.|.||:....:|||.|.||.||||.|:.:::...:|...||:.|..|:||||.:|.
 Frog    87 ITFCSALDEILGGGIPVAKITEICGVPGVGKTQLCMQLAVDVQIPECFGGVAGETVFIDTECSFR 151

Human   149 AERLVEIAES------------------RFPRYFNTEEKLLLTSSKVHLYRELTCD---EVLQRI 192
            .|||::||.:                  :..:.|...|.|    |:::.:   :|.   |:|.:|
 Frog   152 LERLMDIANACVQHCNLIAQGHQDKDHIKAMQTFTLNEIL----SQIYYF---SCHDYIELLAQI 209

Human   193 ESLEEEIIS-KGIKLVILDSVASVVRKEFDAQLQGNLKERNKFLAREASSLKYLAEEFSIPVILT 256
            ..|.:.:.| ..:|||::||:|...|..|:     :|..|.:.|......|..||...::.|:||
 Frog   210 NLLPDFLSSHPKVKLVVIDSIAFPFRHSFE-----DLSLRTRLLNGFGQQLISLAHNCNLAVVLT 269

Human   257 NQITTHLSGALASQADLVSPADDLSLSEGTSGSSCVIAALGNTWSHSVNTRLILQYLDSERRQIL 321
            ||:||.           :.|:|           |.::.|||.:|.|:...||||.: .|::|.:.
 Frog   270 NQMTTK-----------IGPSD-----------SKLVPALGESWGHASTIRLILHW-KSKQRFVT 311

Human   322 IAKSPLAPFTSFVYTIKEEGLVLQVVRTVARVSPRSECWSAADSHPSPTFLIPDVVLRKTRNPRL 386
            :.|||.....:..|.|..:|.                 ..|..:.|....|||      ..|||.
 Frog   312 LCKSPSQKKATVPYGITSQGF-----------------RDAEIAEPEANALIP------ASNPRK 353

Human   387 LPSV 390
            .|.|
 Frog   354 RPRV 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAD51B	NP_001308750.1	Rad51B	91..327	CDD:410901	78/257 (30%)
rad51c	NP_001016923.1	Rad51C	105..316	CDD:410900	72/245 (29%)