Protein Alignment RAD51B and rfs-1

DIOPT Version :10

• Sequence 1: NP_001308750.1
• Gene: RAD51B / 5890
• HGNCID: 9822
• Length: 425
• Species: Homo sapiens
• Sequence 2: NP_001370362.1
• Gene: rfs-1 / 24104262
• WormBaseID: WBGene00004342
• Length: 245
• Species: Caenorhabditis elegans
• Alignment Length: 283
• Identity: 70/283 - (24%)
• Similarity: 104/283 - (36%)
• Gaps: 90/283 - (31%)

Human    63 KMQTAYGIKAQRSADFSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFCIMMS--ILA 125
            |.:|||.:..:..|:  ..||.|.||.||..|.  :..|...||.|..|.||||.|...:  .|.
 Worm     9 KYETAYDLLVRLGAE--RLFLRTCLSILDPVLE--LHPGKCYEIDGDLGVGKTQICYSFAAKFLQ 69

Human   126 TLPTNMGGLEGAVVYIDTESAFSAERLVEIAESRFPRYFNTEEKLLLTSSKVHLYRELTCDEVLQ 190
            |..|...|..||..                        ..|:..||    .:..:...|.:::|.
 Worm    70 TKKTAKMGWIGATP------------------------LRTDHLLL----HIEHFGNQTNEDILD 106

Human   191 RI------------ESLEEEIISKGIKLVILDSVASVV-----RKEFDAQLQGNLKERNKFLARE 238
            ||            :||...:.:..::|||::::.:::     .||....:|.::.||.:.|.:
 Worm   107 RIVCKRVEKIAELQDSLTRFLDTINLQLVIVENIDAILHDTVYHKEMGRSMQSDVVERIRKLTK- 170

Human   239 ASSLKYLAEEFSIPVILTNQITTHLSGALASQADLVSPADDLSLSEGTSGSSCVIAALGNTWSHS 303
                      ..|.|||||.| ||..|         .||                .|||..||..
 Worm   171 ----------LEITVILTNHI-THWRG---------YPA----------------PALGAFWSSQ 199

Human   304 VNTRLILQYL--DSERRQILIAK 324
            :|.|..::..  ||:.|.:...|
 Worm   200 INNRFFIEKRNDDSDIRIVSAMK 222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAD51B	NP_001308750.1	Rad51B	91..327	CDD:410901	59/255 (23%)
rfs-1	NP_001370362.1	P-loop containing Nucleoside Triphosphate Hydrolases	40..214	CDD:476819	54/238 (23%)