Protein Alignment RAC2 and CDC42

DIOPT Version :10

• Sequence 1: NP_002863.1
• Gene: RAC2 / 5880
• HGNCID: 9802
• Length: 192
• Species: Homo sapiens
• Sequence 2: NP_013330.1
• Gene: CDC42 / 850930
• SGDID: S000004219
• Length: 191
• Species: Saccharomyces cerevisiae
• Alignment Length: 192
• Identity: 130/192 - (67%)
• Similarity: 158/192 - (82%)
• Gaps: 1/192 - (0%)

Human     1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYD 65
            ||.:||||||||||||||||||||||.||.:|:|||||||:..||:..:|..|||:|||||||||
Yeast     1 MQTLKCVVVGDGAVGKTCLLISYTTNQFPADYVPTVFDNYAVTVMIGDEPYTLGLFDTAGQEDYD 65

Human    66 RLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLK 130
            ||||||||.|||||:|||::||.|:|||:.||||||.||||..|.::|||::||||||..||||:
Yeast    66 RLRPLSYPSTDVFLVCFSVISPPSFENVKEKWFPEVHHHCPGVPCLVVGTQIDLRDDKVIIEKLQ 130

Human   131 EKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQQKRACSLL 192
            .::|.|||..||..||:|:.:|||:|||||||||||.||||||.|.|.| |..::.:.|::|
Yeast   131 RQRLRPITSEQGSRLARELKAVKYVECSALTQRGLKNVFDEAIVAALEP-PVIKKSKKCAIL 191

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAC2	NP_002863.1	Rac1_like	3..176	CDD:206663	122/172 (71%)
		Effector region. /evidence=ECO:0000255	32..40		6/7 (86%)
CDC42	NP_013330.1	Cdc42	3..177	CDD:206664	123/173 (71%)