Protein Alignment RAC2 and RhoL

DIOPT Version :10

• Sequence 1: NP_002863.1
• Gene: RAC2 / 5880
• HGNCID: 9802
• Length: 192
• Species: Homo sapiens
• Sequence 2: NP_001247003.1
• Gene: RhoL / 41136
• FlyBaseID: FBgn0014380
• Length: 214
• Species: Drosophila melanogaster
• Alignment Length: 189
• Identity: 98/189 - (51%)
• Similarity: 132/189 - (69%)
• Gaps: 10/189 - (5%)

Human     4 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLR 68
            :|..:||||.|||||:||:||.|.||.|||||||||::.|:.||.:..||.||||||||||:|||
  Fly    36 LKITIVGDGMVGKTCMLITYTRNEFPEEYIPTVFDNHACNIAVDDRDYNLTLWDTAGQEDYERLR 100

Human    69 PLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEKK 133
            |||||.|:.||:|:|:.|..|:|||::||:||:||.....|::|||||||||....  ||.
  Fly   101 PLSYPSTNCFLLCYSISSRTSFENVKSKWWPEIRHFSAHVPVVLVGTKLDLRIPNS--EKF---- 159

Human   134 LAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQQKRACSLL 192
               :|..:|..:.|||.:...:||||..::.|:.||:||:|||. .:|....|::|.:|
  Fly   160 ---VTTQEGKKMRKEIHAFNLVECSAKKKQNLQQVFEEAVRAVE-RKPKTTSKQSCKIL 214

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAC2	NP_002863.1	Rac1_like	3..176	CDD:206663	92/171 (54%)
		Effector region. /evidence=ECO:0000255	32..40		7/7 (100%)
RhoL	NP_001247003.1	Rho	36..198	CDD:206641	91/170 (54%)