Protein Alignment RAC2 and Cdc42

DIOPT Version :10

• Sequence 1: NP_002863.1
• Gene: RAC2 / 5880
• HGNCID: 9802
• Length: 192
• Species: Homo sapiens
• Sequence 2: NP_523414.1
• Gene: Cdc42 / 32981
• FlyBaseID: FBgn0010341
• Length: 191
• Species: Drosophila melanogaster
• Alignment Length: 193
• Identity: 134/193 - (69%)
• Similarity: 157/193 - (81%)
• Gaps: 3/193 - (1%)

Human     1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYD 65
            ||.|||||||||||||||||||||||.||.||:|||||||:..||:..:|..|||:|||||||||
  Fly     1 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYD 65

Human    66 RLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLK 130
            ||||||||||||||:|||:|||:|:|||:.||.||:.|||..||.:||||::||||:..|:|||.
  Fly    66 RLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCQKTPFLLVGTQIDLRDENSTLEKLA 130

Human   131 EKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVL-CPQPTRQQKRACSLL 192
            :.|..|||..||..||||:.:|||:|||||||:|||.||||||.|.| .|:||:  ||.|..|
  Fly   131 KNKQKPITMEQGEKLAKELKAVKYVECSALTQKGLKNVFDEAILAALEPPEPTK--KRKCKFL 191

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAC2	NP_002863.1	Rac1_like	3..176	CDD:206663	123/172 (72%)
		Effector region. /evidence=ECO:0000255	32..40		6/7 (86%)
Cdc42	NP_523414.1	Cdc42	3..177	CDD:206664	124/173 (72%)