Protein Alignment RAC2 and cdc42

DIOPT Version :10

• Sequence 1: NP_002863.1
• Gene: RAC2 / 5880
• HGNCID: 9802
• Length: 192
• Species: Homo sapiens
• Sequence 2: NP_593536.1
• Gene: cdc42 / 2543027
• PomBaseID: SPAC110.03
• Length: 192
• Species: Schizosaccharomyces pombe
• Alignment Length: 192
• Identity: 126/192 - (65%)
• Similarity: 152/192 - (79%)
• Gaps: 0/192 - (0%)

Human     1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYD 65
            |..|||||||||||||||||||||||.||.:|:|||||||:..||:..:|..|||:|||||||||
pombe     1 MPTIKCVVVGDGAVGKTCLLISYTTNKFPSDYVPTVFDNYAVTVMIGDEPYTLGLFDTAGQEDYD 65

Human    66 RLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLK 130
            ||||||||||||||:|||:.||||:|||:.||||||.||||..|.::|||::|||||....:||.
pombe    66 RLRPLSYPQTDVFLVCFSVTSPASFENVKEKWFPEVHHHCPGVPCLIVGTQIDLRDDPSVQQKLA 130

Human   131 EKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQQKRACSLL 192
            .:...|:|:.||..||:|:.:|||:|||||||:|||.||||||.|.|.|....::|..|.:|
pombe   131 RQHQHPLTHEQGERLARELGAVKYVECSALTQKGLKNVFDEAIVAALDPPVPHKKKSKCLVL 192

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAC2	NP_002863.1	Rac1_like	3..176	CDD:206663	119/172 (69%)
		Effector region. /evidence=ECO:0000255	32..40		6/7 (86%)
cdc42	NP_593536.1	Cdc42	3..177	CDD:206664	120/173 (69%)