Protein Alignment RAC2 and rac-2

DIOPT Version :10

• Sequence 1: NP_002863.1
• Gene: RAC2 / 5880
• HGNCID: 9802
• Length: 192
• Species: Homo sapiens
• Sequence 2: NP_001040961.1
• Gene: rac-2 / 186939
• WormBaseID: WBGene00004287
• Length: 195
• Species: Caenorhabditis elegans
• Alignment Length: 195
• Identity: 141/195 - (72%)
• Similarity: 167/195 - (85%)
• Gaps: 3/195 - (1%)

Human     1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYD 65
            ||||||||||||||||||||:||||||||||||.||||.||.|||||.:|:||.|||||||:|||
 Worm     1 MQAIKCVVVGDGAVGKTCLLLSYTTNAFPGEYILTVFDTYSTNVMVDGRPINLSLWDTAGQDDYD 65

Human    66 RLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLK 130
            :.|.||:|||||||:||:|.:|||:|||||||:|||.||||:|||||||||.|||:|:||||:|:
 Worm    66 QFRHLSFPQTDVFLVCFALNNPASFENVRAKWYPEVSHHCPNTPIILVGTKADLREDRDTIERLR 130

Human   131 EKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCP---QPTRQQKRACSLL 192
            |::|.|:::.||..:||||.:|||||||||||.|||.|||||||..|.|   ..||.:|..|::|
 Worm   131 ERRLQPVSHTQGYVMAKEIKAVKYLECSALTQIGLKQVFDEAIRTGLTPPQTPQTRAKKSNCTVL 195

Human   193  192
             Worm   196  195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAC2	NP_002863.1	Rac1_like	3..176	CDD:206663	132/172 (77%)
		Effector region. /evidence=ECO:0000255	32..40		6/7 (86%)
rac-2	NP_001040961.1	Rac1_like	3..176	CDD:206663	132/172 (77%)