Protein Alignment RAC1 and CDC42

DIOPT Version :10

• Sequence 1: NP_061485.1
• Gene: RAC1 / 5879
• HGNCID: 9801
• Length: 211
• Species: Homo sapiens
• Sequence 2: NP_013330.1
• Gene: CDC42 / 850930
• SGDID: S000004219
• Length: 191
• Species: Saccharomyces cerevisiae
• Alignment Length: 211
• Identity: 134/211 - (63%)
• Similarity: 159/211 - (75%)
• Gaps: 20/211 - (9%)

Human     1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYD 65
            ||.:||||||||||||||||||||||.||.:|:|||||||:..||:..:|..|||:|||||||||
Yeast     1 MQTLKCVVVGDGAVGKTCLLISYTTNQFPADYVPTVFDNYAVTVMIGDEPYTLGLFDTAGQEDYD 65

Human    66 RLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPII 130
            ||||||||.|                   ||||:|||::||.|||||:.||:|||.||||..|.:
Yeast    66 RLRPLSYPST-------------------DVFLVCFSVISPPSFENVKEKWFPEVHHHCPGVPCL 111

Human   131 LVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAV 195
            :|||::||||||..||||:.::|.|||..||..:|:|:.||||:|||||||||||.||||||.|.
Yeast   112 VVGTQIDLRDDKVIIEKLQRQRLRPITSEQGSRLARELKAVKYVECSALTQRGLKNVFDEAIVAA 176

Human   196 LCPPPVKKRKRKCLLL 211
            |.||.:||.| ||.:|
Yeast   177 LEPPVIKKSK-KCAIL 191

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAC1	NP_061485.1	Rac1_like	3..195	CDD:206663	122/191 (64%)
CDC42	NP_013330.1	Cdc42	3..177	CDD:206664	123/192 (64%)