DRSC/TRiP Functional Genomics Resources

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Protein Alignment RAC1 and Mtl

DIOPT Version :9

Sequence 1:NP_061485.1 Gene:RAC1 / 5879 HGNCID:9801 Length:211 Species:Homo sapiens
Sequence 2:NP_524533.1 Gene:Mtl / 43319 FlyBaseID:FBgn0039532 Length:195 Species:Drosophila melanogaster


Alignment Length:208 Identity:136/208 - (65%)
Similarity:165/208 - (79%) Gaps:19/208 - (9%)


- Green bases have known domain annotations that are detailed below.


Human     4 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLR 68
            |||||||||.|||||:||||||:.|||||:|||||||||.:.||...|:||||||||||||||||
  Fly     7 IKCVVVGDGTVGKTCMLISYTTDCFPGEYVPTVFDNYSAPMQVDTIQVSLGLWDTAGQEDYDRLR 71

Human    69 PLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVG 133
            |||||||                   ||||||:|:.||:|||||.:|||||::||||:.||||||
  Fly    72 PLSYPQT-------------------DVFLICYSVASPSSFENVTSKWYPEIKHHCPDAPIILVG 117

Human   134 TKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCP 198
            ||:|||:|::|:..|.|:.|||:...||..:|.:|.||||:|||||||||||.||:||:||||.|
  Fly   118 TKIDLREDRETLSGLAEQGLTPLKREQGQKLANKIRAVKYMECSALTQRGLKPVFEEAVRAVLRP 182

Human   199 PPVKKRKRKCLLL 211
            .|:|:|:||||::
  Fly   183 EPLKRRQRKCLIM 195

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RAC1NP_061485.1 Rac1_like 3..195 CDD:206663 125/190 (66%)
MtlNP_524533.1 RHO 9..182 CDD:197554 126/191 (66%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0393
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1091615at2759
OrthoFinder 1 1.000 - - FOG0000070
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100633
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X103
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
65.720

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