Protein Alignment RAC1 and RhoL

DIOPT Version :10

• Sequence 1: NP_061485.1
• Gene: RAC1 / 5879
• HGNCID: 9801
• Length: 211
• Species: Homo sapiens
• Sequence 2: NP_001247003.1
• Gene: RhoL / 41136
• FlyBaseID: FBgn0014380
• Length: 214
• Species: Drosophila melanogaster
• Alignment Length: 208
• Identity: 101/208 - (48%)
• Similarity: 131/208 - (62%)
• Gaps: 29/208 - (13%)

Human     4 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLR 68
            :|..:||||.|||||:||:||.|.||.|||||||||::.|:.||.:..||.||||||||||:|||
  Fly    36 LKITIVGDGMVGKTCMLITYTRNEFPEEYIPTVFDNHACNIAVDDRDYNLTLWDTAGQEDYERLR 100

Human    69 PLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVG 133
            |||||.|                   :.||:|:|:.|..|||||::||:||:||...:.|::|||
  Fly   101 PLSYPST-------------------NCFLLCYSISSRTSFENVKSKWWPEIRHFSAHVPVVLVG 146

Human   134 TKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCP 198
            ||||||....  ||.       :|..:|..|.|||.|...:||||..::.|:.||:||:|||...
  Fly   147 TKLDLRIPNS--EKF-------VTTQEGKKMRKEIHAFNLVECSAKKKQNLQQVFEEAVRAVERK 202

Human   199 PPVKKRKRKCLLL 211
            |.... |:.|.:|
  Fly   203 PKTTS-KQSCKIL 214

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAC1	NP_061485.1	Rac1_like	3..195	CDD:206663	95/190 (50%)
RhoL	NP_001247003.1	Rho	36..198	CDD:206641	94/189 (50%)