Protein Alignment RAC1 and Rho1

DIOPT Version :10

• Sequence 1: NP_061485.1
• Gene: RAC1 / 5879
• HGNCID: 9801
• Length: 211
• Species: Homo sapiens
• Sequence 2: NP_477098.1
• Gene: Rho1 / 36775
• FlyBaseID: FBgn0014020
• Length: 192
• Species: Drosophila melanogaster
• Alignment Length: 208
• Identity: 114/208 - (54%)
• Similarity: 140/208 - (67%)
• Gaps: 23/208 - (11%)

Human     5 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRP 69
            |.|:|||||.|||||||.::.:.||..|:||||:||.|::.||||.|.|.|||||||||||||||
  Fly     7 KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRP 71

Human    70 LSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGT 134
            ||||.|                   ||.|:|||:.||.|.||:..||.|||:|.|||.||||||.
  Fly    72 LSYPDT-------------------DVILMCFSVDSPDSLENIPEKWTPEVKHFCPNVPIILVGN 117

Human   135 KLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPP 199
            |.|||:|.:||..|.:.|..|:...:|.|||::|.|..||||||.::.|::.||:.|.||.|
  Fly   118 KKDLRNDPNTIRDLAKMKQEPVKPQEGRAMAEKINAFAYLECSAKSKEGVRDVFETATRAAL--- 179

Human   200 PVKKRKR-KCLLL 211
            .|||||: :||||
  Fly   180 QVKKRKKTRCLLL 192

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAC1	NP_061485.1	Rac1_like	3..195	CDD:206663	103/189 (54%)
Rho1	NP_477098.1	RhoA_like	5..179	CDD:206662	104/190 (55%)