Protein Alignment RAC1 and Cdc42

DIOPT Version :10

• Sequence 1: NP_061485.1
• Gene: RAC1 / 5879
• HGNCID: 9801
• Length: 211
• Species: Homo sapiens
• Sequence 2: NP_523414.1
• Gene: Cdc42 / 32981
• FlyBaseID: FBgn0010341
• Length: 191
• Species: Drosophila melanogaster
• Alignment Length: 210
• Identity: 138/210 - (65%)
• Similarity: 158/210 - (75%)
• Gaps: 20/210 - (9%)

Human     1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYD 65
            ||.|||||||||||||||||||||||.||.||:|||||||:..||:.|:|..|||:|||||||||
  Fly     1 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYD 65

Human    66 RLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPII 130
            ||||||||||                   ||||:|||:|||:|||||:.||.||:.|||..||.:
  Fly    66 RLRPLSYPQT-------------------DVFLVCFSVVSPSSFENVKEKWVPEITHHCQKTPFL 111

Human   131 LVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAV 195
            ||||::||||:..|:|||.:.|..|||..||..:|||:.||||:|||||||:|||.||||||.|.
  Fly   112 LVGTQIDLRDENSTLEKLAKNKQKPITMEQGEKLAKELKAVKYVECSALTQKGLKNVFDEAILAA 176

Human   196 LCPP-PVKKRKRKCL 209
            |.|| |.||||.|.|
  Fly   177 LEPPEPTKKRKCKFL 191

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAC1	NP_061485.1	Rac1_like	3..195	CDD:206663	125/191 (65%)
Cdc42	NP_523414.1	Cdc42	3..177	CDD:206664	126/192 (66%)