Protein Alignment RAC1 and RhoU

DIOPT Version :10

• Sequence 1: NP_061485.1
• Gene: RAC1 / 5879
• HGNCID: 9801
• Length: 211
• Species: Homo sapiens
• Sequence 2: NP_001036266.1
• Gene: RhoU / 31945
• FlyBaseID: FBgn0083940
• Length: 582
• Species: Drosophila melanogaster
• Alignment Length: 212
• Identity: 90/212 - (42%)
• Similarity: 118/212 - (55%)
• Gaps: 27/212 - (12%)

Human     3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRL 67
            :||||:|||||||||.|::||..|.|..|:|||..|.|:|:|.|:..||:|.:.|||||:..|.|
  Fly   392 SIKCVLVGDGAVGKTNLILSYLENRFNPEHIPTASDIYNADVNVNESPVHLTICDTAGQDTLDPL 456

Human    68 RPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILV 132
            |.|.||.                   :||||:|||:|.|.:|..::.||.|:...  ....:|||
  Fly   457 RELCYPD-------------------SDVFLLCFSVVKPETFRAIKTKWAPKFAK--TKAALILV 500

Human   133 GTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLC 197
            ||:.|||...:.:.||:......|:|.....:|..||| ||:|.|:.||..:|.|||.||...|.
  Fly   501 GTQADLRTSPNVLNKLQTNGEEAISYADAWDLATTIGA-KYIETSSATQDKVKDVFDTAIWEGLV 564

Human   198 P---PPVKK--RKRKCL 209
            |   ||...  ||..||
  Fly   565 PTTLPPTPSFWRKLFCL 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAC1	NP_061485.1	Rac1_like	3..195	CDD:206663	82/191 (43%)
RhoU	NP_001036266.1	Wrch_1	393..562	CDD:133330	82/190 (43%)