Protein Alignment RAC1 and cdc42

DIOPT Version :10

• Sequence 1: NP_061485.1
• Gene: RAC1 / 5879
• HGNCID: 9801
• Length: 211
• Species: Homo sapiens
• Sequence 2: NP_593536.1
• Gene: cdc42 / 2543027
• PomBaseID: SPAC110.03
• Length: 192
• Species: Schizosaccharomyces pombe
• Alignment Length: 211
• Identity: 131/211 - (62%)
• Similarity: 156/211 - (73%)
• Gaps: 19/211 - (9%)

Human     1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYD 65
            |..|||||||||||||||||||||||.||.:|:|||||||:..||:..:|..|||:|||||||||
pombe     1 MPTIKCVVVGDGAVGKTCLLISYTTNKFPSDYVPTVFDNYAVTVMIGDEPYTLGLFDTAGQEDYD 65

Human    66 RLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPII 130
            ||||||||||                   ||||:|||:.||||||||:.||:|||.||||..|.:
pombe    66 RLRPLSYPQT-------------------DVFLVCFSVTSPASFENVKEKWFPEVHHHCPGVPCL 111

Human   131 LVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAV 195
            :|||::|||||....:||..:...|:|:.||..:|:|:|||||:|||||||:|||.||||||.|.
pombe   112 IVGTQIDLRDDPSVQQKLARQHQHPLTHEQGERLARELGAVKYVECSALTQKGLKNVFDEAIVAA 176

Human   196 LCPPPVKKRKRKCLLL 211
            |.||...|:|.|||:|
pombe   177 LDPPVPHKKKSKCLVL 192

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAC1	NP_061485.1	Rac1_like	3..195	CDD:206663	120/191 (63%)
cdc42	NP_593536.1	Cdc42	3..177	CDD:206664	121/192 (63%)