Protein Alignment RAB5C and VPS21

DIOPT Version :10

• Sequence 1: NP_001238968.1
• Gene: RAB5C / 5878
• HGNCID: 9785
• Length: 249
• Species: Homo sapiens
• Sequence 2: NP_014732.1
• Gene: VPS21 / 854256
• SGDID: S000005615
• Length: 210
• Species: Saccharomyces cerevisiae
• Alignment Length: 205
• Identity: 111/205 - (54%)
• Similarity: 142/205 - (69%)
• Gaps: 8/205 - (3%)

Human    52 ICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERY 116
            :...|||||||:||||||:|||||...|.|.:|.|||||||||.|.:::.||||||||||||||:
Yeast     5 VTSIKLVLLGEAAVGKSSIVLRFVSNDFAENKEPTIGAAFLTQRVTINEHTVKFEIWDTAGQERF 69

Human   117 HSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADL---ASKRAVE 178
            .||||||||.||||:||||:|...:|.:|::|||||..|||.:|:|||.|||.|:   ..:|.|.
Yeast    70 ASLAPMYYRNAQAALVVYDVTKPQSFIKARHWVKELHEQASKDIIIALVGNKIDMLQEGGERKVA 134

Human   179 FQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKLPKN--EPQNATG--APGRNRGVDLQ-EN 238
            .:|.:..|::..|||.||||||..|||::|:.|.:|:|..  |.||:..  ....|:.|||. .|
Yeast   135 REEGEKLAEEKGLLFFETSAKTGENVNDVFLGIGEKIPLKTAEEQNSASNERESNNQRVDLNAAN 199

Human   239 NPASRSQCCS 248
            :..|.:..||
Yeast   200 DGTSANSACS 209

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB5C	NP_001238968.1	Rab5_related	54..216	CDD:206653	99/164 (60%)
VPS21	NP_014732.1	Rab5_related	7..172	CDD:206653	99/164 (60%)