Protein Alignment RAB5C and Rab18

DIOPT Version :10

• Sequence 1: NP_001238968.1
• Gene: RAB5C / 5878
• HGNCID: 9785
• Length: 249
• Species: Homo sapiens
• Sequence 2: NP_524744.2
• Gene: Rab18 / 44360
• FlyBaseID: FBgn0015794
• Length: 197
• Species: Drosophila melanogaster
• Alignment Length: 194
• Identity: 76/194 - (39%)
• Similarity: 118/194 - (60%)
• Gaps: 8/194 - (4%)

Human    56 KLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLA 120
            ||:::|||.||||||:.|||:.:|.:..:.|||..|.::.:.:|....|..:|||||.||:.||.
  Fly     7 KLLVIGESGVGKSSLIRRFVENKFDQNHDVTIGMDFKSKVMQVDGIDYKVALWDTAGAERFRSLT 71

Human   121 PMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQA-SPNIVIALAGNKADLASKRAVEFQEAQA 184
            |.:||.|..||:|||||:.|:..:.:.|:.||...: :|||.|.:.|||.|  .:|.|:.:|.:.
  Fly    72 PSFYRKALGAILVYDITSRDSLVKLETWLAELDSYSDNPNIAIIVVGNKID--EERVVDREEGRK 134

Human   185 YADDNSLLFMETSAKTAMNVNEIFMAIAKKLPKNEPQNATGAPGRNRGVDLQENN--PASRSQC 246
            :|..:..||:|||||....|:::|..:.:|:..:|..|...|   :.|:|:..:.  .||.|.|
  Fly   135 FARKHRALFIETSAKCDQFVSDVFKDVVEKIVSSEYFNNGNA---SAGLDIASDRDLEASASTC 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB5C	NP_001238968.1	Rab5_related	54..216	CDD:206653	67/160 (42%)
Rab18	NP_524744.2	Rab18	6..165	CDD:206656	66/159 (42%)