Protein Alignment RAB5C and Rab26

DIOPT Version :10

• Sequence 1: NP_001238968.1
• Gene: RAB5C / 5878
• HGNCID: 9785
• Length: 249
• Species: Homo sapiens
• Sequence 2: NP_001097658.1
• Gene: Rab26 / 40359
• FlyBaseID: FBgn0086913
• Length: 410
• Species: Drosophila melanogaster
• Alignment Length: 256
• Identity: 90/256 - (35%)
• Similarity: 145/256 - (56%)
• Gaps: 27/256 - (10%)

Human     7 SPSPLSASLHSTSPHP-----HALWTTTAGRAMAGRGGAARPNGPAAGNKICQF----KLVLLGE 62
            :|:|:       :|.|     .|.....||||:.....:::     |..:..:|    |:::||:
  Fly   168 APAPV-------APGPGSEGASATLCKNAGRALIRMISSSK-----APEEEDEFDIMGKVIMLGD 220

Human    63 SAVGKSSLVLRFVKGQF-HEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRG 126
            |.|||:||::||..|:: ..|..||:|..|..:.|.:|.|.||.:|||||||||:.|:...|||.
  Fly   221 SGVGKTSLLIRFRDGRYVPSYFLSTVGIDFRNKVVVVDGTRVKLQIWDTAGQERFRSVTHAYYRD 285

Human   127 AQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADLA-SKRAVEFQEAQAYADDNS 190
            |.|.:::||:||..|:...:.|:.|::..|..::||.|.|||||.: |:|.|:.::.:....:::
  Fly   286 AHALLLLYDVTNKTTYDNIRAWLGEIREYAQEDVVIVLIGNKADCSGSERQVKREDGERLGREHN 350

Human   191 LLFMETSAKTAMNVNEIFMAIAKKLPKNEPQNATGAPGRNRGVDLQENNPASRSQC--CSN 249
            :.||||||||.:||...|.|:|::|.....::  |..|:....|...:|..:||.|  |.|
  Fly   351 VPFMETSAKTGLNVELSFTAVARQLKSRGYEH--GDDGKFNVHDFVRDNTKARSVCAQCRN 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB5C	NP_001238968.1	Rab5_related	54..216	CDD:206653	70/167 (42%)
Rab26	NP_001097658.1	Rab26	214..407	CDD:206695	77/194 (40%)