Protein Alignment RAB5C and Rab19

DIOPT Version :10

• Sequence 1: NP_001238968.1
• Gene: RAB5C / 5878
• HGNCID: 9785
• Length: 249
• Species: Homo sapiens
• Sequence 2: NP_523970.1
• Gene: Rab19 / 38930
• FlyBaseID: FBgn0015793
• Length: 219
• Species: Drosophila melanogaster
• Alignment Length: 197
• Identity: 73/197 - (37%)
• Similarity: 112/197 - (56%)
• Gaps: 4/197 - (2%)

Human    55 FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSL 119
            ||:||:|:...||:.:|.||..|.:.|...:|||..|..:|:.::...:|.:|||||||||:.::
  Fly    22 FKIVLIGDCGTGKTCIVDRFKTGNYIERHGNTIGVDFSMKTIAVEGKQIKLQIWDTAGQERFRTI 86

Human   120 APMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADLASKRAVEFQEAQA 184
            ...|||.|...::|||||...:|:..:.|::|::|..:.|::|.|.|||.||..:|.|:|:||:.
  Fly    87 TQSYYRSANGVLIVYDITKRSSFSNLQKWIEEVRRYTASNVLIILVGNKCDLEEQREVDFEEARQ 151

Human   185 YAD--DNSLLFMETSAKTAMNVNEIFMAIAKKLPKNEPQNATGAPGRNRGVDLQENNP-ASRSQC 246
            ...  ...|..||||||..|||.:.|..:|.:|.:....|.......|. :.|.:..| .|.|..
  Fly   152 MCQYIPEILFVMETSAKENMNVEDAFRCLANELKRQHDANNVEEVPENT-ITLGQGKPLKSCSSS 215

Human   247 CS 248
            |:
  Fly   216 CN 217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB5C	NP_001238968.1	Rab5_related	54..216	CDD:206653	65/162 (40%)
Rab19	NP_523970.1	Rab19	19..184	CDD:133267	65/161 (40%)