Protein Alignment RAB5C and Rab2

DIOPT Version :10

• Sequence 1: NP_001238968.1
• Gene: RAB5C / 5878
• HGNCID: 9785
• Length: 249
• Species: Homo sapiens
• Sequence 2: NP_477090.1
• Gene: Rab2 / 35577
• FlyBaseID: FBgn0014009
• Length: 213
• Species: Drosophila melanogaster
• Alignment Length: 207
• Identity: 77/207 - (37%)
• Similarity: 125/207 - (60%)
• Gaps: 14/207 - (6%)

Human    55 FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSL 119
            ||.:::|::.||||.|:|:|...:|....:.|||..|..:.:.:|...:|.:||||||||.:.|:
  Fly     7 FKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQEAFRSI 71

Human   120 APMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADLASKRAVEFQEAQA 184
            ...|||||..|::|||||..:||.....|:::.::.::.|:||.|.|||:||.|:|.|:.:|.:|
  Fly    72 TRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSNSNMVIMLIGNKSDLDSRREVKKEEGEA 136

Human   185 YADDNSLLFMETSAKTAMNVNEIFMAIAKKLPKNEPQNATGAPGRNRGVDL-QENNP-------- 240
            :|.::.|:||||||:||.||.|.|:..||::.:...:..........|:.: |:::|
  Fly   137 FAREHGLVFMETSARTAANVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGQQHSPTNPSLPGA 201

Human   241 -----ASRSQCC 247
                 |:.|.||
  Fly   202 GGAAGAANSGCC 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB5C	NP_001238968.1	Rab5_related	54..216	CDD:206653	70/160 (44%)
Rab2	NP_477090.1	PLN03108	1..213	CDD:178655	75/205 (37%)