Protein Alignment RAB5C and rab-5

DIOPT Version :10

• Sequence 1: NP_001238968.1
• Gene: RAB5C / 5878
• HGNCID: 9785
• Length: 249
• Species: Homo sapiens
• Sequence 2: NP_492481.1
• Gene: rab-5 / 172755
• WormBaseID: WBGene00004268
• Length: 208
• Species: Caenorhabditis elegans
• Alignment Length: 219
• Identity: 164/219 - (74%)
• Similarity: 182/219 - (83%)
• Gaps: 17/219 - (7%)

Human    34 MAGR-GGAARPNGPAAGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVC 97
            ||.| .|.|||.||   |:.|||||||||||||||||||||||||||||||||||||||||||||
 Worm     1 MAARNAGTARPGGP---NRTCQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVC 62

Human    98 LDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVI 162
            |||.|:|||||||||||||||||||||||||||||||||||.::|.:|||||||||||||||||:
 Worm    63 LDDATIKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQESFQKAKNWVKELQRQASPNIVM 127

Human   163 ALAGNKADLASKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKLP----KNEPQNA 223
            ||||||||:|:||.||::||.|||:||:||||||||||:||||:||||||||||    :.||
 Worm   128 ALAGNKADVANKRTVEYEEANAYAEDNALLFMETSAKTSMNVNDIFMAIAKKLPIGPAQGEP--- 189

Human   224 TGAPGRNRGVDLQENNPASRSQCC 247
            ||.      ||:.:.....:..||
 Worm   190 TGT------VDMNQPQQQQKGSCC 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB5C	NP_001238968.1	Rab5_related	54..216	CDD:206653	143/161 (89%)
rab-5	NP_492481.1	Rab5_related	19..181	CDD:206653	143/161 (89%)