Protein Alignment MAP4K2 and sid1

DIOPT Version :9

• Sequence 1: XP_024304397.1
• Gene: MAP4K2 / 5871
• HGNCID: 6864
• Length: 860
• Species: Homo sapiens
• Sequence 2: NP_593564.1
• Gene: sid1 / 2542746
• PomBaseID: SPAC9G1.09
• Length: 471
• Species: Schizosaccharomyces pombe
• Alignment Length: 419
• Identity: 139/419 - (33%)
• Similarity: 215/419 - (51%)
• Gaps: 78/419 - (18%)

Human    16 FELLQRVGAGTYGDVYKARDTVTSELAAVKIVKLDPG-DDISSLQQEITILRECRHPNVVAYIGS 79
            :.||:::|:|::|.|:|||:.|:.::.|:|.:.|:.| |||:.::||:.:|..|...||:.|.|.
pombe     9 YTLLRKLGSGSFGVVWKARENVSGDIIAIKQIDLETGIDDITDIEQEVFMLSNCNSSNVIQYYGC 73

Human    80 YLRNDRLWICMEFCGGGSLQEIYHATGPLEERQIAYVCREALKGLHHLHSQGKIHRDIKGANLLL 144
            ::....|||.||...|||:..:. ..|.|.|:.|:.:.||.|.||::||.|.|||||||.||:||
pombe    74 FVDGYTLWILMEHMDGGSVSGLL-KMGRLNEQVISIILREVLYGLNYLHGQNKIHRDIKAANILL 137

Human   145 TLQ-GDVKLADFGVSGELTASVAKRRSFIGTPYWMAPEVAAVERKGGYNELCDVWALGITAIELG 208
            :.. |:||||||||:.:|:.:.::|.:|:|||:||||||.   ::..|....|:|:|||||||:.
pombe   138 SSSTGNVKLADFGVAAQLSNAASRRHTFVGTPFWMAPEVI---QQTSYGLAADIWSLGITAIEMA 199

Human   209 ELQPPLFHLHPMRALMLMSKSSFQPPKLRDKTRWTQNFHHFLKLALTKNPKKRPTAEKLLQHPF- 272
            ...||...:||||.:..:.:|  :||||.|  .::..|..|:...|..||..|.:|::||||||
pombe   200 NGIPPRATMHPMRVIFEIPQS--EPPKLDD--HFSPTFRDFVSCCLDLNPNMRWSAKELLQHPFI 260

Human   273 ----TTQQLPRALL---TQLLDKASDPHL-----------------GTPSPEDCELETYDMFPDT 313
                |.:.:...|:   .:|.|.:....|                 |....||...||......|
pombe   261 KSAGTVKDIIPLLVQKENKLFDDSDQSVLEETINNTLKPFEEPIAEGNADIEDWTFETVKKSDST 325

Human   314 ------------IHSRGQHGPAERTPSEIQFHQVKFGAPRRKETDPLNEPWEEEWTLLGKEELSG 366
                        |.|:.:    |..||.|::                     .|.|::..:....
pombe   326 VLGNTSIPKNSIISSQNK----EELPSSIKY---------------------LEKTIMSDQATPH 365

Human   367 SLLQSVQE--ALEERSLTIRSASEFQVPH 393
            ...:|:.|  :...:|||    |:|.:.|
pombe   366 PFSKSLSEKGSSYHKSLT----SDFAMKH 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAP4K2	XP_024304397.1	STKc_MAP4K3_like	16..272	CDD:270788	110/257 (43%)
		CNH	528..840	CDD:214481
sid1	NP_593564.1	STKc_MST3_like	7..279	CDD:270786	114/277 (41%)
		S_TKc	9..260	CDD:214567	111/258 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010