Protein Alignment BCAT2 and BAT2

DIOPT Version :10

• Sequence 1: NP_001181.2
• Gene: BCAT2 / 587
• HGNCID: 977
• Length: 392
• Species: Homo sapiens
• Sequence 2: NP_012682.1
• Gene: BAT2 / 853613
• SGDID: S000003909
• Length: 376
• Species: Saccharomyces cerevisiae
• Alignment Length: 368
• Identity: 171/368 - (46%)
• Similarity: 229/368 - (62%)
• Gaps: 20/368 - (5%)

Human    34 AADLQLEMTQKPHKKPGPGEPLVFGKTFTDHMLMVEWN-DKGWGQPRIQPFQNLTLHPASSSLHY 97
            |:.:::..||.. .||.|...|||||:||||||..||. :||||.|.|:|:|||:|.|::...||
Yeast     8 ASKVKITTTQHA-SKPKPNSELVFGKSFTDHMLTAEWTAEKGWGTPEIKPYQNLSLDPSAVVFHY 71

Human    98 SLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDA 162
            :.:|||||||::..|.::.:|||.:||.||.:||.|:|||:||..||:..|.:||:.||..||:.
Yeast    72 AFELFEGMKAYRTVDNKITMFRPDMNMKRMNKSAQRICLPTFDPEELITLIGKLIQQDKCLVPEG 136

Human   163 AGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGN 227
            .|.|||:||.|||....||||.|.||||:||.||||.|:..| ...|.|.|.....|||.||.|:
Yeast   137 KGYSLYIRPTLIGTTAGLGVSTPDRALLYVICCPVGPYYKTG-FKAVRLEATDYATRAWPGGCGD 200

Human   228 YKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLTEVGTMN-IFVYWTHEDGVLELVTPPLNGV 291
            .|||.||.|.||.|.:|..||.:|.|||:||::.:||||||| .||:...:.|..||||.||:|.
Yeast   201 KKLGANYAPCVLPQLQAASRGYQQNLWLFGPNNNITEVGTMNAFFVFKDSKTGKKELVTAPLDGT 265

Human   292 ILPGVVRQSLLDMAQTW---GEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYK 353
            ||.||.|.|:|::|:..   .|:.:.||..|:.::....:.|.:.|.||||||..|.|:..|.:|
Yeast   266 ILEGVTRDSILNLAKERLEPSEWTISERYFTIGEVTERSKNGELLEAFGSGTAAIVSPIKEIGWK 330

Human   354 DRNLHIPTM---ENGPELILRFQKELKE----IQYGIRAH-EW 388
            ...::||.:   :.||     ..||:.:    ||||...| .|
Yeast   331 GEQINIPLLPGEQTGP-----LAKEVAQWINGIQYGETEHGNW 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BCAT2	NP_001181.2	BCAT_beta_family	87..382	CDD:238798	138/305 (45%)
BAT2	NP_012682.1	BCAT_beta_family	61..361	CDD:238798	138/305 (45%)