Protein Alignment BCAT2 and Bcat

DIOPT Version :10

• Sequence 1: NP_001181.2
• Gene: BCAT2 / 587
• HGNCID: 977
• Length: 392
• Species: Homo sapiens
• Sequence 2: NP_572884.1
• Gene: Bcat / 32297
• FlyBaseID: FBgn0030482
• Length: 443
• Species: Drosophila melanogaster
• Alignment Length: 361
• Identity: 181/361 - (50%)
• Similarity: 254/361 - (70%)
• Gaps: 4/361 - (1%)

Human    32 FKAADLQLEMT--QKPHKKPGPGEPLVFGKTFTDHMLMVEWNDK--GWGQPRIQPFQNLTLHPAS 92
            |:|:.:.:.:.  ::...||...|.|.||:.||||||.:.::..  ||.:|.|.|.:||.:|||:
  Fly    78 FRASQISVRLAAPEQLQPKPDNDEELGFGRLFTDHMLKIYYHKSLGGWQRPEITPLENLVMHPAA 142

Human    93 SSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKD 157
            ..|||:::|||||||::|.|.::|:|||.:||:||..:|.|..||:|:..|.::|:.||:.:|.:
  Fly   143 KVLHYAVELFEGMKAYRGVDGKIRIFRPDMNMNRMNLAAQRSGLPTFEGKEFVQCLSRLLSIDSE 207

Human   158 WVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWV 222
            |||.....|||:||.|||.:|:|||:....|||:.||.|||:||..||...|||||||:::|||.
  Fly   208 WVPHTDTASLYIRPTLIGIDPTLGVASSDSALLYTILSPVGSYFKTGSSGAVSLLADPSYVRAWP 272

Human   223 GGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPP 287
            |||||.|:|.||.||:.||:||..:|.:|||||||.|||||||||||||:::.::.|..||||||
  Fly   273 GGVGNRKMGSNYAPTINVQKEAAAKGLQQVLWLYGEDHQLTEVGTMNIFMFFVNDQGEQELVTPP 337

Human   288 LNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILY 352
            |:|:||||:.|.|:|.|.:.||:|:|.|..|||..:...|.:||:.|:||:||||.|.||:||.|
  Fly   338 LSGLILPGITRDSILRMTRQWGKFKVSEANITMPMVCELLNQGRLLELFGAGTACVVSPVNRISY 402

Human   353 KDRNLHIPTMENGPELILRFQKELKEIQYGIRAHEW 388
            ..::|:|||||....:....::.|.:||||...|.|
  Fly   403 LGQDLYIPTMEQEKPVHELIRETLTDIQYGRVDHPW 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BCAT2	NP_001181.2	BCAT_beta_family	87..382	CDD:238798	156/294 (53%)
Bcat	NP_572884.1	BCAT_beta_family	138..432	CDD:238798	156/293 (53%)