Protein Alignment BCAT2 and eca39

DIOPT Version :10

• Sequence 1: NP_001181.2
• Gene: BCAT2 / 587
• HGNCID: 977
• Length: 392
• Species: Homo sapiens
• Sequence 2: NP_595180.2
• Gene: eca39 / 2540831
• PomBaseID: SPBC428.02C
• Length: 427
• Species: Schizosaccharomyces pombe
• Alignment Length: 382
• Identity: 171/382 - (44%)
• Similarity: 228/382 - (59%)
• Gaps: 22/382 - (5%)

Human    21 LCGPRRYASSSFKAADLQLEMTQKPHKKPGPGEPLVFGKTFTDHMLMVEWN-DKGWGQPRIQPFQ 84
            |.||:...||..|..::: |:...|..|     .|.||:.||||||:::|| :|||..|.|.||.
pombe    54 LHGPKPMDSSHIKVTNVK-ELKPLPEWK-----SLKFGENFTDHMLIMKWNREKGWSTPEIVPFG 112

Human    85 NLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIR 149
            .|..|||||..||..:.|||||||:.:....|||||..|.:|||.:..|:.|||||..||.|.||
pombe   113 KLCFHPASSVFHYGFECFEGMKAFRDEKGVPRLFRPIKNAERMLSTGTRISLPSFDPAELAEIIR 177

Human   150 RLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPGGSVTPVSLLAD 214
            :.:..:..||||..|.|||:||..||.:.:|||.....|:|:||..|||.|:..| ...|.|...
pombe   178 KFVAHENRWVPDQRGYSLYIRPTFIGTDEALGVHHCDNAMLYVIASPVGPYYSSG-FKAVKLCCS 241

Human   215 PAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDG 279
            ...:|||.||.|:|||||||.|:||.|:||.|:|..|:|||||.:..:|||||||.|..|.:::|
pombe   242 EESVRAWPGGTGHYKLGGNYAPSVLPQKEAAKKGYAQILWLYGDEDYITEVGTMNCFTVWINKNG 306

Human   280 VLELVTPPLNGVILPGVVRQSLLDMAQT------WGEFRVVERTITMKQLLRALEEGRVREVFGS 338
            ..|::|.||:|:|||||.|.|:|::.:.      |   ::.|...:||::.:|.:|||:.||||:
pombe   307 EKEIITAPLDGMILPGVTRDSILEICRERLAPKGW---KITEGKYSMKEVAQASKEGRLLEVFGA 368

Human   339 GTACQVCPVHRILYKDRNLHIPT---MENGPELILRFQKELKEIQYGIRAHE-WMFP 391
            |||..|.||..|.||.....||.   .|.|| :.....|.:.:||||...:. |..|
pombe   369 GTAALVSPVKAINYKGTEYEIPMPEGQEAGP-ITSEISKWILDIQYGKEPNNPWSVP 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BCAT2	NP_001181.2	BCAT_beta_family	87..382	CDD:238798	139/303 (46%)
eca39	NP_595180.2	BCAT_beta_family	117..414	CDD:238798	139/301 (46%)