Protein Alignment RAB5B and VPS21

DIOPT Version :10

• Sequence 1: NP_001401387.1
• Gene: RAB5B / 5869
• HGNCID: 9784
• Length: 296
• Species: Homo sapiens
• Sequence 2: NP_014732.1
• Gene: VPS21 / 854256
• SGDID: S000005615
• Length: 210
• Species: Saccharomyces cerevisiae
• Alignment Length: 207
• Identity: 112/207 - (54%)
• Similarity: 141/207 - (68%)
• Gaps: 8/207 - (3%)

Human    97 SKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQE 161
            :.:...|||||||:||||||:|||||...|.|.:|.|||||||||.|.:::.|||||||||||||
Yeast     3 TSVTSIKLVLLGEAAVGKSSIVLRFVSNDFAENKEPTIGAAFLTQRVTINEHTVKFEIWDTAGQE 67

Human   162 RYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIALAGNKADL---ANKRM 223
            |:.||||||||.||||:||||:|..::|.:|:.|||||..|||..|:|||.|||.|:   ..:|.
Yeast    68 RFASLAPMYYRNAQAALVVYDVTKPQSFIKARHWVKELHEQASKDIIIALVGNKIDMLQEGGERK 132

Human   224 VEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKLP--KSEPQNLGGAAGRSRG--VDLHE 284
            |..||.:..|::..|||.||||||..||||:||.|.:|:|  .:|.||.......|..  |||:.
Yeast   133 VAREEGEKLAEEKGLLFFETSAKTGENVNDVFLGIGEKIPLKTAEEQNSASNERESNNQRVDLNA 197

Human   285 QSQ-QNKSQCCS 295
            .:. .:.:..||
Yeast   198 ANDGTSANSACS 209

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB5B	NP_001401387.1	Rab5_related	101..263	CDD:206653	102/164 (62%)
VPS21	NP_014732.1	Rab5_related	7..172	CDD:206653	102/164 (62%)