Protein Alignment RAB5B and Rab5

DIOPT Version :10

• Sequence 1: NP_001401387.1
• Gene: RAB5B / 5869
• HGNCID: 9784
• Length: 296
• Species: Homo sapiens
• Sequence 2: NP_523457.1
• Gene: Rab5 / 33418
• FlyBaseID: FBgn0014010
• Length: 219
• Species: Drosophila melanogaster
• Alignment Length: 223
• Identity: 159/223 - (71%)
• Similarity: 184/223 - (82%)
• Gaps: 13/223 - (5%)

Human    80 LAMTSRS-------TA-RPNGQPQASKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGA 136
            :|.|.||       || ||||..| :|.|||||||||||||||||||||||||||||||||||||
  Fly     1 MATTPRSGGASGTGTAQRPNGTSQ-NKSCQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGA 64

Human   137 AFLTQSVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQR 201
            |||||::|::||.||||||||||||||||||||||||||||||||||.||::|.|||||||||.:
  Fly    65 AFLTQTICIEDTVVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDIQNQDSFQRAKTWVKELHK 129

Human   202 QASPSIVIALAGNKADLANKRMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKLPKSE 266
            ||||:||||||||||||:|.|:||::||:.||::|.||||||||||.|||||:||||||||||::
  Fly   130 QASPNIVIALAGNKADLSNIRVVEFDEAKQYAEENGLLFMETSAKTGMNVNDIFLAIAKKLPKND 194

Human   267 PQNLGGAAGRSRGVDLHEQSQQNKSQCC 294
            ..|..|.:.|..|.:.:..:    :.||
  Fly   195 GANNQGTSIRPTGTETNRPT----NNCC 218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB5B	NP_001401387.1	Rab5_related	101..263	CDD:206653	137/161 (85%)
Rab5	NP_523457.1	Rab5_related	29..191	CDD:206653	137/161 (85%)