Protein Alignment RAB5B and rab-5

DIOPT Version :10

• Sequence 1: NP_001401387.1
• Gene: RAB5B / 5869
• HGNCID: 9784
• Length: 296
• Species: Homo sapiens
• Sequence 2: NP_492481.1
• Gene: rab-5 / 172755
• WormBaseID: WBGene00004268
• Length: 208
• Species: Caenorhabditis elegans
• Alignment Length: 216
• Identity: 164/216 - (75%)
• Similarity: 184/216 - (85%)
• Gaps: 10/216 - (4%)

Human    80 LAMTSRSTARPNGQPQASKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVC 144
            :|..:..||||.|   .::.||||||||||||||||||||||||||||||||||||||||||:||
 Worm     1 MAARNAGTARPGG---PNRTCQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVC 62

Human   145 LDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVI 209
            |||.|:|||||||||||||||||||||||||||||||||||||:|.:||.|||||||||||:||:
 Worm    63 LDDATIKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQESFQKAKNWVKELQRQASPNIVM 127

Human   210 ALAGNKADLANKRMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKLPKSEPQNLGGAA 274
            ||||||||:||||.||||||.|||:||:||||||||||:|||||:|:|||||||      :|.|.
 Worm   128 ALAGNKADVANKRTVEYEEANAYAEDNALLFMETSAKTSMNVNDIFMAIAKKLP------IGPAQ 186

Human   275 GRSRG-VDLHEQSQQNKSQCC 294
            |...| ||:::..||.|..||
 Worm   187 GEPTGTVDMNQPQQQQKGSCC 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB5B	NP_001401387.1	Rab5_related	101..263	CDD:206653	144/161 (89%)
rab-5	NP_492481.1	Rab5_related	19..181	CDD:206653	144/161 (89%)