Protein Alignment RAB5A and Rab5a

DIOPT Version :10

• Sequence 1: NP_004153.2
• Gene: RAB5A / 5868
• HGNCID: 9783
• Length: 215
• Species: Homo sapiens
• Sequence 2: NP_073183.1
• Gene: Rab5a / 64633
• RGDID: 620936
• Length: 215
• Species: Rattus norvegicus
• Alignment Length: 215
• Identity: 210/215 - (97%)
• Similarity: 213/215 - (99%)
• Gaps: 0/215 - (0%)

Human     1 MASRGATRPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLD 65
            ||:||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat     1 MANRGATRPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLD 65

Human    66 DTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVIAL 130
            |||||||||||||||||||||||||||||||||||||||||||:|||||||||||||||||||||
  Rat    66 DTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFSRAKNWVKELQRQASPNIVIAL 130

Human   131 SGNKADLANKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKLPKNEPQNPGANSAR 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   131 SGNKADLANKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKLPKNEPQNPGANSAR 195

Human   196 GRGVDLTEPTQPTRNQCCSN 215
            |||||||||.||.|:|||||
  Rat   196 GRGVDLTEPAQPARSQCCSN 215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB5A	NP_004153.2	Rab5_related	20..182	CDD:206653	160/161 (99%)
		Switch 1. /evidence=ECO:0000269|PubMed:20534488, ECO:0007744|PDB:3MJH	44..56		11/11 (100%)
		Switch 2. /evidence=ECO:0000269|PubMed:20534488, ECO:0007744|PDB:3MJH	77..93		15/15 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	181..215		30/33 (91%)
Rab5a	NP_073183.1	Rab5_related	20..182	CDD:206653	160/161 (99%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P20339	44..56		11/11 (100%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P20339	77..93		15/15 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	181..215		30/33 (91%)