Protein Alignment RAB5A and rab5ab

DIOPT Version :10

• Sequence 1: NP_004153.2
• Gene: RAB5A / 5868
• HGNCID: 9783
• Length: 215
• Species: Homo sapiens
• Sequence 2: NP_957264.1
• Gene: rab5ab / 393945
• ZFINID: ZDB-GENE-040122-3
• Length: 216
• Species: Danio rerio
• Alignment Length: 215
• Identity: 198/215 - (92%)
• Similarity: 205/215 - (95%)
• Gaps: 1/215 - (0%)

Human     1 MASR-GATRPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCL 64
            ||.| |||||||||||||||||||||||||||||||||||||||||||||||||||||||||:||
Zfish     1 MAGRGGATRPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTLCL 65

Human    65 DDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVIA 129
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish    66 DDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVIA 130

Human   130 LSGNKADLANKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKLPKNEPQNPGANSA 194
            |:|||||||||||:|||:|||||||||||||||||||||||:||||||||||||||||..|||:|
Zfish   131 LAGNKADLANKRALDFQDAQSYADDNSLLFMETSAKTSMNVSEIFMAIAKKLPKNEPQPAGANTA 195

Human   195 RGRGVDLTEPTQPTRNQCCS 214
            |.|||||||..||.:..|||
Zfish   196 RNRGVDLTETAQPAKGPCCS 215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB5A	NP_004153.2	Rab5_related	20..182	CDD:206653	156/161 (97%)
		Switch 1. /evidence=ECO:0000269|PubMed:20534488, ECO:0007744|PDB:3MJH	44..56		11/11 (100%)
		Switch 2. /evidence=ECO:0000269|PubMed:20534488, ECO:0007744|PDB:3MJH	77..93		15/15 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	181..215		24/34 (71%)
rab5ab	NP_957264.1	Rab5_related	21..183	CDD:206653	156/161 (97%)