Protein Alignment RAB2A and Rab9

DIOPT Version :10

• Sequence 1: NP_002856.1
• Gene: RAB2A / 5862
• HGNCID: 9763
• Length: 212
• Species: Homo sapiens
• Sequence 2: NP_609966.1
• Gene: Rab9 / 35221
• FlyBaseID: FBgn0032782
• Length: 256
• Species: Drosophila melanogaster
• Alignment Length: 161
• Identity: 61/161 - (37%)
• Similarity: 98/161 - (60%)
• Gaps: 5/161 - (3%)

Human     6 LFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRS 70
            |.|.:|:||.|||||.||.:|...|::..:..||||||..:.|.:||::..||||||||||.||:
  Fly    12 LLKVVILGDGGVGKSALLTRFVANRYEENNFHTIGVEFMNKDIVVDGERYTLQIWDTAGQERFRA 76

Human    71 ITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSN---SNMVIMLIGNKSDLES-RREVKK 131
            :...:|||:...||.|.:..||:...|..|..:...:::   .....:::|||:|:.: :|:|..
  Fly    77 LRTPFYRGSDICLLCYALDDRDSLKGLGVWRNEFLNYADVDQDKFPFIVVGNKNDIPAQKRQVSS 141

Human   132 EEGEAFAREHGL-IFMETSAKTASNVEEAFI 161
            :..:.:..|..: ..:|||:|.|:||.:||:
  Fly   142 DAVQQWCAEQKVACHIETSSKAATNVTDAFV 172

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB2A	NP_002856.1	PLN03108	1..188	CDD:178655	61/161 (38%)
		Required for interaction with PRKCI. /evidence=ECO:0000269|PubMed:14570876	2..19		7/12 (58%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P61106	37..42		3/4 (75%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P61106	63..72		6/8 (75%)
Rab9	NP_609966.1	Rab9	8..178	CDD:206697	61/161 (38%)