Protein Alignment RAB2A and Rab10

DIOPT Version :10

• Sequence 1: NP_002856.1
• Gene: RAB2A / 5862
• HGNCID: 9763
• Length: 212
• Species: Homo sapiens
• Sequence 2: NP_523419.1
• Gene: Rab10 / 33025
• FlyBaseID: FBgn0015789
• Length: 204
• Species: Drosophila melanogaster
• Alignment Length: 168
• Identity: 86/168 - (51%)
• Similarity: 118/168 - (70%)
• Gaps: 0/168 - (0%)

Human     3 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES 67
            |..|||.::|||:||||:|:|.:|:|..|......|||::|..:.:.:.||:||||||||||||.
  Fly     6 YDLLFKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIWDTAGQER 70

Human    68 FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKE 132
            |.:||.||||||.|.:||||||...:|.::..||.:..:|:|.::..|::|||.|:..:|.|.||
  Fly    71 FHTITTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVNKE 135

Human   133 EGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEK 170
            .|||.|||||:.|||||||:..|:|.||...|:.|.:|
  Fly   136 RGEAIAREHGIRFMETSAKSNINIERAFCELAEAILDK 173

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB2A	NP_002856.1	PLN03108	1..188	CDD:178655	86/168 (51%)
		Required for interaction with PRKCI. /evidence=ECO:0000269|PubMed:14570876	2..19		9/15 (60%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P61106	37..42		3/4 (75%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P61106	63..72		5/8 (63%)
Rab10	NP_523419.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	84/165 (51%)