|
Human 3838 PKTDGGSETKKQRSKRTQRTGEKAAPRSKKRKKDEEEKQAMYSSTDTFTHLKQQNNLSNP----P 3898
|.:...:.|::..:....::|... .:|.|...::.| |...:::....|.|::. |
Yeast 66 PHSSNNASTRQYYATNNSQSGPYV-----NKKSDISSRRGM--SQSRYSNSNVHNTLASSSGSLP 123
Human 3899 TPPASLPPTPPPMACQ------------------------KMANGFATTEELAGKAGVLVSHEVT 3939
|..|.|....||...: ||.:..||.:|.:. ..:.|.
Yeast 124 TESALLLQQRPPSVLRYNTDNLKSKFHYFDPIKGEFFNKDKMLSWKATDKEFSE-----TGYYVV 183
Human 3940 KTLGPKPFQLPFRPQDDLLARALAQGPKTVDVPASLPTPPHNNQEELRIQDHCGDRDTPDSFVPS 4004
|.|....|:...: |.:.| :.:
Yeast 184 KELQDGQFKFKIK---------------------------HRHPE-----------------IKA 204
Human 4005 SSPESVVGVEVSRYPDLSLVKEEPPEPVPSPIIPILPSTAGKSSESR--RNDIKTEPGTLYFASP 4067
|.|.:..|: .|:||.:..| ||.:...|...|....
Yeast 205 SDPRNENGI----------------------------MTSGKVATHRKCRNSLILLPRISYDRYS 241
Human 4068 FGPSPNGPRSGLISVAITLHP------TAAENIS--SVVAAFSDLLHVRIPNSYEVSSAPDVPSM 4124
.||.| |..|.::| |..::|| :....:.::.| :|..:.|
Yeast 242 LGPPP--------SCEIVVYPAQDSTTTNIQDISIKNYFKKYGEISH------FEAFNDP----- 287
Human 4125 GLVSSHRINPGLEYRQHLLLRGPPPGSANPPRLVSSYRLKQPNVPFPPTSNG--LSGYKD----S 4183
|..|....:|:......|..|.....:...:::.. |:| :.|:|. :
Yeast 288 --------NSALPLHVYLIKYASSDGKINDAAKAAFSAVRKHE------SSGCFIMGFKFEVILN 338
Human 4184 SHGIAESAALRPQWCCHCKVVILGSGVRKS--------------FKDLTLLNK-------DSRES 4227
.|.|..:...:.......|:..|...::|: .||:||..: .|..|
Yeast 339 KHSILNNIISKFVEINVKKLQKLQENLKKAKEKEAENEKAKELQGKDITLPKEPKVDTLSHSSGS 403
Human 4228 TKRVEKDIVFCSNN-----------------------------C----------FILYSSTAQAK 4253
.||:..|::...|| | :|:::..|.|:
Yeast 404 EKRIPYDLLGVVNNRPVLHVSKIFVAKHRFCVEDFKYKLRGYRCAKFIDHPTGIYIIFNDIAHAQ 468
Human 4254 NSENKESIPSLPQSPMRETPSK-AFHQYSNNISTLDVHCLPQLPEK--------ASPPASPPIAF 4309
...|.||......|..|..|.. .||. .||:...: :|...:.||.:
Yeast 469 TCSNAESGNLTIMSRSRRIPILIKFHL-----------ILPRFQNRTRFNKSSSSSNSTNVPIKY 522
Human 4310 PPAFEAAQVEAKPDELKVTVKLKPRLRAVHGGFEDCRPLNKKWRGMKWKKWSIHIVIPKGTFKPP 4374
|:|.:.::.|.| :..:.|.| ::|:.|.|....|.
Yeast 523 ---------ESKEEFIEATAK------------QILKDLEK----------TLHVDIKKRLIGPT 556
Human 4375 CEDEID-----EFLKK-----------LGTSLKPDPVPKDYRKCCFCHEEGD------GLTDGPA 4417
..|.:| |.|.| :.:.:..|.:.: .||.. ||..|.|
Yeast 557 VFDALDHANFPELLAKRELKEKEKRQQIASKIAEDELKR--------KEEAKRDFDLFGLYGGYA 613
Human 4418 RLLNLDLDLWVHLNCALWSTEVYETQAGALINVELALRRGLQ-MKCVFCHKTGATSGCHRFRCTN 4481
:....:|.. |.:.||..|.:...: |..|:: |..:...:|.:
Yeast 614 KSNKRNLKR--HNSLALDHTSLKRKK----------LSNGIKPMAHLLNEETDS----------- 655
Human 4482 IYHFTCAIKAQCMFFKDKTMLCPMHKPKGI------HEQELSYFAVFRRVYVQRDEVRQIASIVQ 4540
|:.|.| ..:|| |::| ||....:|..:
Yeast 656 ---------------KETTPL----NDEGITRVSKEHDEE--------------DENMTSSSSEE 687
Human 4541 RGER--DHTFRVGSL-------IFHTIGQLLPQQ--------MQAFHSPKAL-FPVGYEASRLYW 4587
..|. |..|:..|. ..|.|..|:|.| ..:.:.|.|. .| ..:|.
Yeast 688 EEEEAPDKKFKSESEPTTPESDHLHGIKPLVPDQNGSSDVLDASSMYKPTATEIP-----EPVYP 747
Human 4588 STRYANRRCRYLCSIE----EKDGRPVFVIRIVEQGHEDLVLSDISPK---GVWD---KILEPVA 4642
...|..:..:.|.|:: .||...:.:::.:...:...|..:.|.. .:|. |:||
Yeast 748 PEEYDLKYSQTLSSMDLQNAIKDEEDMLILKQLLSTYTPTVTPETSAALEYKIWQSRRKVLE--- 809
Human 4643 CVRKKSEMLQ------LFPAYLKGEDLFGLTVSAVARIAESLPGVEACENYTFRYGRNPLMELPL 4701
.:|:...| ||.:.|:....| ......:||:.|. .||.....| :..||
Yeast 810 --EEKASDWQIELNGTLFDSELQPGSSF--KAEGFRKIADKLK-----INYLPHRRR---VHQPL 862
Human 4702 -AVN---------PTGCAR-----SEPKMSAHVKRFVLRPHTLNST----STSKSFQSTVTGELN 4747
.|| |..|.| .||..|. |..::|: ::::.||..:..:
Yeast 863 NTVNIHNERNEYTPELCQREESSNKEPSDSV--------PQEVSSSRDNRASNRRFQQDIEAQ-- 917
Human 4748 APYSKQFVHSKS-----SQYRKMKTEWKSNVYLARSRIQGLGLYAARDIEKHTMVIEYIGTIIRN 4807
|..:.::| :|..|. |..|..|||.|...||||...|....|:|||:|..||.
Yeast 918 ----KAAIGTESELLSLNQLNKR----KKPVMFARSAIHNWGLYALDSIAAKEMIIEYVGERIRQ 974
Human 4808 EVANRKEKLYESQNRG-VYMFRMDNDHVIDATLTGGPARYINHSCAPNCVAEVVTFERGHKIIIS 4871
.||..:||.|.....| .|:||:|.:.|||||..||.||:|||.|.|||.|:::......:|:|.
Yeast 975 PVAEMREKRYLKNGIGSSYLFRVDENTVIDATKKGGIARFINHCCDPNCTAKIIKVGGRRRIVIY 1039
Human 4872 SSRRIQKGEELCYDYKFDFE-DDQHKIPCHCGAVNCRKWMN 4911
:.|.|...|||.|||||:.| ||:.::||.|||.||:.::|
Yeast 1040 ALRDIAASEELTYDYKFEREKDDEERLPCLCGAPNCKGFLN 1080
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