| Sequence 1: | NP_149017.2 | Gene: | BBS4 / 585 | HGNCID: | 969 | Length: | 519 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_477246.2 | Gene: | Tmtc3 / 37401 | FlyBaseID: | FBgn0020312 | Length: | 926 | Species: | Drosophila melanogaster |
| Alignment Length: | 377 | Identity: | 83/377 - (22%) |
|---|---|---|---|
| Similarity: | 159/377 - (42%) | Gaps: | 48/377 - (12%) |
- Green bases have known domain annotations that are detailed below.
|
Human 80 EGNIQESLELFQTCAVLSPQSADNLKQVARSLFLLGKHKAAIEVYNEA-AKLNQKDWEISHNLGV 143
Human 144 CYIYLKQF-------NKAQDQLHNALNLNRHDLT--------YIMLGKIHLLEGDLDKAIEVYKK 193
Human 194 AVEFSPENTELLTTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKAILAAGSMMQTHGDFD---VA 255
Human 256 LTKYRVVACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQY 320
Human 321 ASAFHFLSAAINFQPK-------MGELYMLLAVALTNLEDIENAKRAYAEAVHLDKCNPLVNLNY 378
Human 379 AVLLYNQGEKKNALAQYQEMEKKVSLLKDNSSLEFDSEMVEMAQKLGAALQV 430 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| BBS4 | NP_149017.2 | Required for localization to centrosomes | 1..66 | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..25 | ||||
| TPR_11 | <18..400 | CDD:330823 | 75/345 (22%) | ||
| TPR repeat | 36..61 | CDD:276809 | |||
| TPR 1 | 67..100 | 6/19 (32%) | |||
| TPR repeat | 68..95 | CDD:276809 | 6/14 (43%) | ||
| Interaction with PCM1. /evidence=ECO:0000269|PubMed:15107855 | 101..337 | 59/261 (23%) | |||
| TPR repeat | 101..129 | CDD:276809 | 6/28 (21%) | ||
| TPR repeat | 134..164 | CDD:276809 | 7/36 (19%) | ||
| TPR repeat | 169..196 | CDD:276809 | 9/34 (26%) | ||
| TPR repeat | 202..229 | CDD:276809 | 6/26 (23%) | ||
| TPR repeat | 236..264 | CDD:276809 | 6/30 (20%) | ||
| TPR repeat | 270..298 | CDD:276809 | 7/27 (26%) | ||
| TPR repeat | 303..333 | CDD:276809 | 8/29 (28%) | ||
| Required for localization to centrosomes | 338..519 | 18/93 (19%) | |||
| TPR repeat | 338..365 | CDD:276809 | 5/26 (19%) | ||
| TPR repeat | 372..397 | CDD:276809 | 2/24 (8%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 440..519 | ||||
| Tmtc3 | NP_477246.2 | DUF1736 | 323..396 | CDD:369859 | |
| PEP_TPR_lipo | <513..871 | CDD:274350 | 80/365 (22%) | ||
| TPR repeat | 514..542 | CDD:276809 | 6/14 (43%) | ||
| TPR repeat | 547..591 | CDD:276809 | 9/43 (21%) | ||
| TPR repeat | 598..625 | CDD:276809 | 7/26 (27%) | ||
| TPR repeat | 630..660 | CDD:276809 | 9/29 (31%) | ||
| TPR repeat | 665..693 | CDD:276809 | 7/27 (26%) | ||
| TPR repeat | 737..764 | CDD:276809 | 7/26 (27%) | ||
| TPR repeat | 803..834 | CDD:276809 | 5/36 (14%) | ||
| TPR repeat | 839..867 | CDD:276809 | 7/43 (16%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG1124 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.810 | |||||