Protein Alignment JAM2 and jam2

DIOPT Version :9

• Sequence 1: NP_001257337.1
• Gene: JAM2 / 58494
• HGNCID: 14686
• Length: 312
• Species: Homo sapiens
• Sequence 2: NP_001072218.1
• Gene: jam2 / 779665
• XenbaseID: XB-GENE-493973
• Length: 295
• Species: Xenopus tropicalis
• Alignment Length: 280
• Identity: 146/280 - (52%)
• Similarity: 192/280 - (68%)
• Gaps: 12/280 - (4%)

Human    19 VALGYHKA------YGFSAPKDQQVVTAVEYQEAILACKTP-KKTVSSRLEWKKL--GRSVSFVY 74
            :.|||..|      :|.....|...|...|:.|.||:||.. :|....||||||:  ...:||:|
 Frog     8 IFLGYFAALCCKETFGVYVSSDNSNVQVQEFGEIILSCKYKLEKEHPVRLEWKKVVPNGDISFIY 72

Human    75 YQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSC 139
            |..||..|.:.|||||:.:|.:||.||:|:|||||||:||.: .::.:|..:.|:|||||.||.|
 Frog    73 YNNTLAADLRGRAEMIESSIWLKNATRADSGKYRCEVTAPKD-NKSFQEIVIDLKVLVAPGVPVC 136

Human   140 EVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTV 204
            :||.||:|||.|||:|::.||.||.||.|:|:||.|..||...::.||||||:|:.:||||||||
 Frog   137 DVPPSAMSGTAVELKCRESEGFPASEYRWYKNGILLAINPAPNARLTNSSYTVNSASGTLQFNTV 201

Human   205 SKLDTGEYSCEARNSVG-YRRCPGKRMQVDDLNISGIIAAVVVVALVISVCGLGVCYAQRKGYFS 268
            :|:|||||.|||.|.:| .::|..:|:||||||::||||.|||||||:..|||||.|||||||||
 Frog   202 AKMDTGEYYCEASNGIGKSQKCAVRRLQVDDLNVAGIIAGVVVVALVMLFCGLGVFYAQRKGYFS 266

Human   269 KETSFQKSNSSSKATTMSEN 288
            |..:..| .:|.|..:..||
 Frog   267 KGNASGK-EASQKTASQKEN 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JAM2	NP_001257337.1	IG_like	35..130	CDD:214653	43/97 (44%)
		Ig	151..225	CDD:319273	43/74 (58%)
jam2	NP_001072218.1	Ig	53..128	CDD:386229	35/75 (47%)
		Ig_3	134..215	CDD:372822	50/80 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	108	1.000	Domainoid score	I28469
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10929
Inparanoid	1	1.050	292	1.000	Inparanoid score	I10768
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG40756
OrthoDB	1	1.010	-	-		D1034087at2759
OrthoFinder	1	1.000	-	-		FOG0001462
OrthoInspector	1	1.000	-	-		oto154169
Panther	1	1.100	-	-	LDO	PTHR44663
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11523
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.080