Protein Alignment JAM2 and jam2a

DIOPT Version :9

• Sequence 1: NP_001257337.1
• Gene: JAM2 / 58494
• HGNCID: 14686
• Length: 312
• Species: Homo sapiens
• Sequence 2: NP_001091734.1
• Gene: jam2a / 100005261
• ZFINID: ZDB-GENE-031204-3
• Length: 307
• Species: Danio rerio
• Alignment Length: 272
• Identity: 121/272 - (44%)
• Similarity: 172/272 - (63%)
• Gaps: 25/272 - (9%)

Human    32 PKDQQVVTAVEYQEAILAC--KTPKKTVSSRLEWKKLG--RSVSFVYYQQTLQGDFKNRAEMIDF 92
            ||    |...|:.:|.|:|  ||.|.| :.|:|||:..  :.||||||.:...|.|::||::...
Zfish    26 PK----VEVHEFSDAELSCEFKTEKDT-NPRIEWKRKDKEKDVSFVYYGERFVGPFQDRADIEGA 85

Human    93 NIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQD 157
            .:|::.||::|||:|||||||||: ..:|.|..|||.|||.|..|||:||||||:|:.|||||:|
Zfish    86 TVRLRRVTQADAGEYRCEVSAPSD-SISLGETNVTLRVLVPPQTPSCDVPSSALTGSQVELRCRD 149

Human   158 KEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVG- 221
            :...|...|||:||      |..|..:..|::||:|..||.|.|.|||:.|.|:|.|||:|.||
Zfish   150 RHSIPPAVYTWYKD------NRALPIRHPNATYTVNEFTGVLMFQTVSRSDAGQYHCEAKNGVGP 208

Human   222 YRRCPGKRMQVDDLNISGIIAAVVVVALVISVCGLGVCYAQRKGYFSKE--TSF------QKSNS 278
            .:.|....||:||||::.:::|||:|.:::.:|..|||.|.|:||||:.  .||      ..::.
Zfish   209 PKSCQHTHMQIDDLNVAAVVSAVVLVCVILVLCAFGVCLAHRQGYFSRHRGRSFWIPHCHGVTHI 273

Human   279 SSKATTMSENVQ 290
            ||:....||:.|
Zfish   274 SSQNLNPSEHTQ 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JAM2	NP_001257337.1	IG_like	35..130	CDD:214653	43/98 (44%)
		Ig	151..225	CDD:319273	34/74 (46%)
jam2a	NP_001091734.1	IG_like	26..119	CDD:214653	42/98 (43%)
		Ig	28..123	CDD:299845	43/96 (45%)
		Ig_2	129..211	CDD:290606	44/87 (51%)
		IG_like	136..207	CDD:214653	36/76 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C194326265
Domainoid	1	1.000	75	1.000	Domainoid score	I30811
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	1	1.000	-	-
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1034087at2759
OrthoFinder	1	1.000	-	-		FOG0001462
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_116405
Panther	1	1.100	-	-	LDO	PTHR44663
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	1	1.500	-	-
	11	11.350