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Protein Alignment PYGB and Glyp

DIOPT Version :10

Sequence 1:	NP_002853.2	Gene:	PYGB / 5834	HGNCID:	9723	Length:	843	Species:	Homo sapiens
Sequence 2:	NP_722762.1	Gene:	Glyp / 33386	FlyBaseID:	FBgn0004507	Length:	844	Species:	Drosophila melanogaster

Alignment Length:	838	Identity:	607/838 - (72%)
Similarity:	728/838 - (86%)	Gaps:	0/838 - (0%)

- Green bases have known domain annotations that are detailed below.

Human     1 MAKPLTDSEKRKQISVRGLAGLGDVAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLV 65
            |:||.:|:::||||||||:|.:|:|.||:|:||||||:||||||||:|.|||:||||:||:|::|
  Fly     1 MSKPQSDADRRKQISVRGIAEVGNVTEVKKNFNRHLHYTLVKDRNVSTLRDYYFALANTVKDNMV 65

Human    66 GRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQNACDEAIYQLGLDLEELEEIEEDA 130
            ||||||||||||:||||:||||||:||||:|.|||:|||:|:.|:||:||||||:|.|||:||||
  Fly    66 GRWIRTQQHYYEKDPKRVYYLSLEYYMGRSLTNTMINLGIQSECEEAMYQLGLDIENLEEMEEDA 130

Human   131 GLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWEKARP 195
            |||||||||||||||||||||||||||||||||:|||.|||.||.||||.|||||||||||||||
  Fly   131 GLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFAQKIKNGEQVEEPDDWLRYGNPWEKARP 195

Human   196 EYMLPVHFYGRVEHTPDGVKWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLQDFNV 260
            |:||||:|||||..||:|.||:|||.|.|||||.|:|||.||.|||:||||||:|.||.|:.||.
  Fly   196 EFMLPVNFYGRVIDTPEGKKWVDTQRVFAMPYDNPIPGYNNNHVNTLRLWSAKSPIDFNLKFFND 260

Human   261 GDYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRT 325
            ||||:||||||||||||||||||||||||||||||||||:.||||||||||:|:||||.|:.||.
  Fly   261 GDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFMCAATLQDIIRRYKASKFGSREAVRN 325

Human   326 CFETFPDKVAIQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPV 390
            .|:.||||||||||||||:|:||||||||||.|.:.|:|||:||.::||||||||||||||||||
  Fly   326 TFDHFPDKVAIQLNDTHPSLAIPELMRILVDEEHLTWEKAWDITVRSCAYTNHTVLPEALERWPV 390

Human   391 SMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKRINMAHLCVIGSHAVNG 455
            |:.|.:|||||:|||.||..|:::|...||.|:||:||||::||...||||||||.::|||||||
  Fly   391 SLLESILPRHLQIIYHINFLHMENVKKKFPDDLDRMRRMSMVEEDGEKRINMAHLSIVGSHAVNG 455

Human   456 VARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLADTIVEKIGEEFLTDLSQLK 520
            ||.|||:|:|.|:|.||||:||:||||||||||||||||||||||:|.|.||||:|:...|.||.
  Fly   456 VAAIHSQILKDSLFHDFYEMEPQKFQNKTNGITPRRWLLLCNPGLSDLIAEKIGDEWPVHLDQLV 520

Human   521 KLLPLVSDEVFIRDVAKVKQENKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVV 585
            .|.....|..|.|:||:||||||||.:|.|||:|.||||||||||:.||||||||||||||||::
  Fly   521 ALKKWAKDPNFQRNVARVKQENKLKLAAILEKDYGVKINPSSMFDIQVKRIHEYKRQLLNCLHII 585

Human   586 TLYNRIKRDPAKAFVPRTVMIGGKAAPGYHMAKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYR 650
            |||||||:||...|.|||:||||||||||::||.||||:.::|:|||:||:|||:||||||||||
  Fly   586 TLYNRIKKDPTANFTPRTIMIGGKAAPGYYVAKQIIKLICAVGNVVNNDPIVGDKLKVIFLENYR 650

Human   651 VSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLR 715
            |:||||::||||||:|||||||||||||||||.|||||||||:||||||||||.|.:|:||||:.
  Fly   651 VTLAEKIMPAADLSEQISTAGTEASGTGNMKFQLNGALTIGTLDGANVEMAEEMGLDNIFIFGMT 715

Human   716 VEDVEALDRKGYNAREYYDHLPELKQAVDQISSGFFSPKEPDCFKDIVNMLMHHDRFKVFADYEA 780
            |::||||.:|||||.:||:..||:||.:|||..|||||..|:.||:|.::|:.:|.:.:.|||:|
  Fly   716 VDEVEALKKKGYNAYDYYNANPEVKQVIDQIQGGFFSPGNPNEFKNIADILLKYDHYYLLADYDA 780

Human   781 YMQCQAQVDQLYRNPKEWTKKVIRNIACSGKFSSDRTITEYAREIWGVEPSDLQIPPP 838
            |::.|..|.:.|:|..:|.:..|.|||.||||||||||.|||||||||||:..::|.|
  Fly   781 YIKAQDLVSKTYQNQAKWLEMSINNIASSGKFSSDRTIAEYAREIWGVEPTWEKLPAP 838

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.