| Sequence 1: | NP_006496.4 | Gene: | PVR / 5817 | HGNCID: | 9705 | Length: | 417 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_525059.2 | Gene: | kirre / 31292 | FlyBaseID: | FBgn0028369 | Length: | 956 | Species: | Drosophila melanogaster |
| Alignment Length: | 342 | Identity: | 85/342 - (24%) |
|---|---|---|---|
| Similarity: | 131/342 - (38%) | Gaps: | 75/342 - (21%) |
- Green bases have known domain annotations that are detailed below.
|
Human 27 GDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWARHGESGSMAVFHQTQGPSYSESKR 91
Human 92 LEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQGS---RSVDIWLRVLAKPQN------ 147
Human 148 ----TAEVQKVQLTGEPVPMARCVSTGGRPPAQITWHSDLGGMPNTS----QVPGFLSGTVTVTS 204
Human 205 LWILVPSSQVDGKNVTCKVEH---ESFEKPQLLTVNLTVYYPPEVSISGYDNNWYLGQ----NEA 262
Human 263 TLTCDARSNPEPTGYNW----------STTMGPLPPFAVAQGAQLLIRPVDKPINTTLI-CNVTN 316
Human 317 ALGARQAELTVQVKEGP 333 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| PVR | NP_006496.4 | IgV_1_Nectin-2_NecL-5_like_CD112_CD155 | 29..141 | CDD:409581 | 30/114 (26%) |
| FR1 | 29..52 | CDD:409581 | 7/22 (32%) | ||
| Ig strand A | 29..33 | CDD:409581 | 0/3 (0%) | ||
| Ig strand A' | 35..39 | CDD:409581 | 0/3 (0%) | ||
| Ig strand B | 44..52 | CDD:409581 | 5/7 (71%) | ||
| CDR1 | 53..61 | CDD:409581 | 2/7 (29%) | ||
| FR2 | 62..68 | CDD:409581 | 2/5 (40%) | ||
| Ig strand C | 63..68 | CDD:409581 | 2/4 (50%) | ||
| CDR2 | 69..86 | CDD:409581 | 2/16 (13%) | ||
| Ig strand C' | 76..81 | CDD:409581 | 1/4 (25%) | ||
| Ig strand C' | 83..86 | CDD:409581 | 0/2 (0%) | ||
| FR3 | 87..127 | CDD:409581 | 10/39 (26%) | ||
| Ig strand D | 91..97 | CDD:409581 | 2/5 (40%) | ||
| Ig strand E | 105..112 | CDD:409581 | 2/6 (33%) | ||
| Ig strand F | 119..127 | CDD:409581 | 2/7 (29%) | ||
| CDR3 | 128..131 | CDD:409581 | 1/2 (50%) | ||
| Ig strand G | 131..141 | CDD:409581 | 4/12 (33%) | ||
| FR4 | 132..141 | CDD:409581 | 3/11 (27%) | ||
| IgC1_2_Nectin-2_Necl-5_like | 145..241 | CDD:409500 | 27/112 (24%) | ||
| Ig strand A | 145..151 | CDD:409500 | 2/15 (13%) | ||
| Ig strand B | 162..169 | CDD:409500 | 2/6 (33%) | ||
| Ig strand C | 174..180 | CDD:409500 | 3/5 (60%) | ||
| Ig strand C' | 182..184 | CDD:409500 | 0/1 (0%) | ||
| Ig strand D | 187..195 | CDD:409500 | 1/11 (9%) | ||
| Ig strand E | 200..208 | CDD:409500 | 2/7 (29%) | ||
| Ig strand F | 218..225 | CDD:409500 | 2/6 (33%) | ||
| Ig strand G | 231..237 | CDD:409500 | 2/5 (40%) | ||
| Ig3_Nectin-5_like | 244..329 | CDD:409524 | 21/99 (21%) | ||
| Ig strand A | 244..250 | CDD:409524 | 2/5 (40%) | ||
| Ig strand B | 262..266 | CDD:409524 | 1/3 (33%) | ||
| Ig strand C | 276..281 | CDD:409524 | 2/14 (14%) | ||
| Ig strand C' | 283..286 | CDD:409524 | 0/2 (0%) | ||
| Ig strand D | 289..294 | CDD:409524 | 0/4 (0%) | ||
| Ig strand E | 295..301 | CDD:409524 | 1/5 (20%) | ||
| Ig strand F | 306..316 | CDD:409524 | 2/10 (20%) | ||
| Ig strand G | 319..329 | CDD:409524 | 1/9 (11%) | ||
| DYNLT1 binding | 368..372 | ||||
| ITIM motif | 396..401 | ||||
| kirre | NP_525059.2 | IG_like | 88..182 | CDD:214653 | 30/109 (28%) |
| Ig strand B | 99..103 | CDD:409552 | 3/3 (100%) | ||
| Ig strand E | 144..148 | CDD:409552 | 2/3 (67%) | ||
| Ig strand F | 158..163 | CDD:409552 | 2/4 (50%) | ||
| C2-set_2 | 189..279 | CDD:400489 | 23/97 (24%) | ||
| Ig strand C | 219..223 | CDD:409416 | 2/3 (67%) | ||
| Ig strand E | 251..255 | CDD:409416 | 1/3 (33%) | ||
| Ig strand F | 265..270 | CDD:409416 | 2/4 (50%) | ||
| Ig strand G | 280..283 | CDD:409416 | 0/2 (0%) | ||
| Ig_2 | 307..379 | CDD:464026 | 17/84 (20%) | ||
| Ig | 382..462 | CDD:472250 | 1/1 (100%) | ||
| Ig strand B | 399..403 | CDD:409353 | |||
| Ig strand C | 412..417 | CDD:409353 | |||
| Ig strand F | 441..446 | CDD:409353 | |||
| Ig strand G | 455..458 | CDD:409353 | |||
| Ig | 466..561 | CDD:472250 | |||
| Ig strand B | 482..486 | CDD:409353 | |||
| Ig strand C | 496..500 | CDD:409353 | |||
| Ig strand E | 529..533 | CDD:409353 | |||
| Ig strand F | 543..548 | CDD:409353 | |||
| Ig strand G | 556..559 | CDD:409353 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||