Protein Alignment PTPRR and CG42327

DIOPT Version :10

• Sequence 1: NP_002840.2
• Gene: PTPRR / 5801
• HGNCID: 9680
• Length: 657
• Species: Homo sapiens
• Sequence 2: NP_001036706.2
• Gene: CG42327 / 41401
• FlyBaseID: FBgn0259227
• Length: 1429
• Species: Drosophila melanogaster
• Alignment Length: 513
• Identity: 131/513 - (25%)
• Similarity: 200/513 - (38%)
• Gaps: 136/513 - (26%)

Human   268 EIHLSPITLQP---ALSEAKTVHSMVQPEQAPKVL---NVVVDPQGRGAPEIKATTATSVCPSPF 326
            |..|:..|:||   :|.:..|..:...|  ||.|.   :.|.....|.:..:...|.|:...||.
  Fly   919 ETPLTTTTMQPVEISLLDDSTTTTTTTP--APPVYFESSTVASTTIRSSTTMLPETTTASTQSPS 981

Human   327 KMKP----------------------------------IG------------LQERRGSNVS--- 342
            :|.|                                  ||            |..:|....|
  Fly   982 EMPPTFMAPYPNELDHMQTNAQDNGTDVNVIIAITVSVIGVVALILLVAFLYLMRKRQKQTSYGQ 1046

Human   343 ----LTLDMSSLGNIEPFVSIPTPREK-------------VAMEYLQSASRILTRSQLRDVVASS 390
                ::||..||.|:....|:   |.|             .|.:.......:||.|:|...|...
  Fly  1047 RCRPVSLDAYSLDNVSVLGSV---RRKGRDMRASKRTYGNAAFDDPSLRHNLLTASELARFVERR 1108

Human   391 HLLQSEFMEIPMNFVDPKEIDIPRHGTKNRYKTILPNPLSRVCLRPKNVTDSLSTYINANYIRGY 455
            ..:..||.::|.......|:. |....||||..::|.|.:||.|: :...|..:.||||||:||.
  Fly  1109 SDVFEEFRDVPQIIARADEVP-PGCEDKNRYANVIPLPETRVVLQ-RQGDDDKTEYINANYVRGP 1171

Human   456 SGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKN-EKCVLYWP-----EKRGIYGK 514
            ......:||.|.|:.:|..|||:|:|::.|.||:..|.|.|.. |:|..|.|     :....||.
  Fly  1172 RDAPNYYIACQAPLESTTSDFWRMIWEQQSRVIIQATDLSENGIERCAEYLPPSATLDNHSSYGD 1236

Human   515 VEVLVISVNECDNYTIRNLVLKQ--GSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVE----- 572
            .:|.:......|.|.|..||||:  |..::.:.|||| .||:...|....|::.::|:..
  Fly  1237 YQVTLKHREVKDRYAISTLVLKRVDGEESRELTHYWY-KWPEAGVPAEEAPIIAMLLEARSSLKS 1300

Human   573 ----------------EDRLASQG--------------------------RGPVVVHCSAGIGRT 595
                            |..:.:.|                          :||:.||||.|.|||
  Fly  1301 YSLEQANELREKSATLETSMDADGSKAEAGSTSSHEINGNISSRSGTRSQQGPLTVHCSPGTGRT 1365

Human   596 GCFIATSIGCQQLK-EEGVVDALSIVCQLRMDRGGMVQTSEQYEFVHHALCLYESRLS 652
            |..||:.:..:.|: .:..||...:|..:|..|...|||.|||||::....:|.::::
  Fly  1366 GTIIASDMAIRSLETPKRSVDIPQLVYYVRRGRASAVQTKEQYEFIYKVASMYAAKIT 1423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTPRR	NP_002840.2	R-PTPc-R	417..642	CDD:350459	87/280 (31%)
CG42327	NP_001036706.2	PTPc	1134..1415	CDD:214550	87/282 (31%)